{"id":"W3040701062","doi":"10.1681/asn.2020030306","title":"Transcriptional Changes in Kidney Allografts with Histology of Antibody-Mediated Rejection without Anti-HLA Donor-Specific Antibodies","year":2020,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"FP7 Health; Horizon 2020 Framework Programme; Novartis; KU Leuven; H2020 Societal Challenges; Fonds Wetenschappelijk Onderzoek; Vlaamse regering; European Commission; Agence Nationale de la Recherche","keywords":"Antibody; Human leukocyte antigen; Histology; Donor specific antibodies; Kidney; Immunology; Medicine; Kidney transplantation; Graft rejection; Transplantation; Pathology; Antigen; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002405256,0.0001109867,0.0002091408,0.0005278675,0.0001710122,0.0004084698,0.000103341,0.0002030222,0.001280106],"category_scores_gemma":[0.0005102828,0.00009689571,0.0002030235,0.0004621769,0.0001742061,0.0001570888,0.0002022378,0.0001971303,0.0002254499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002162008,"about_ca_system_score_gemma":0.0001877881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006046644,"about_ca_topic_score_gemma":0.0008980514,"domain_scores_codex":[0.9997637,0.00003268057,0.00001914093,0.00008266116,0.00004349014,0.00005832425],"domain_scores_gemma":[0.9995389,0.00008903835,0.0001928485,0.00004011983,0.00006805785,0.0000710967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001098786,0.00008632818,0.7673959,0.00006209151,0.00006489367,0.0001992093,0.0002110869,0.0001626873,0.2244881,0.00007503235,0.0002082933,0.005947747],"study_design_scores_gemma":[0.00000475348,0.0001399974,0.9883272,0.000004340402,0.00003166635,0.0003463736,0.0002663893,0.0003689528,0.009989211,0.00004371427,0.000472643,0.000004801648],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988366,0.0001676972,0.0002347106,0.00001833468,0.0000050978,0.000003516068,0.0005041271,0.00000785167,0.0002220075],"genre_scores_gemma":[0.9985456,0.0001061029,0.0002922214,0.00003071157,0.000007260718,0.00001350395,0.0007143868,0.000003095446,0.0002871206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001280106,"threshold_uncertainty_score":0.004282355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02461542265606041,"score_gpt":0.2861100429381901,"score_spread":0.2614946202821297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}