{"id":"W3040701672","doi":"10.1111/jth.14998","title":"Endothelial characteristics in healthy endothelial colony forming cells; generating a robust and valid ex vivo model for vascular disease","year":2020,"lang":"en","type":"article","venue":"Journal of Thrombosis and Haemostasis","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute; Landsteiner Foundation for Blood Transfusion Research; CSL Behring","keywords":"Ex vivo; Endothelial stem cell; Vascular disease; In vivo; Medicine; Biology; Internal medicine; In vitro; Biotechnology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002683609,0.0001704552,0.0003735881,0.00004284657,0.0001214522,0.00005462921,0.0001030062,0.00009199928,0.000008464932],"category_scores_gemma":[0.00007606536,0.0001506443,0.0001870299,0.00004636283,0.00005027162,0.0000161367,0.00007316857,0.00008528383,1.871403e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002193856,"about_ca_system_score_gemma":0.0001471169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009287552,"about_ca_topic_score_gemma":0.00001242795,"domain_scores_codex":[0.9988849,0.00003968777,0.000460617,0.0002435985,0.0001400743,0.0002310877],"domain_scores_gemma":[0.9992257,0.00002490085,0.0002853106,0.00009794364,0.0001082986,0.0002578897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.003121752,0.0002548058,0.01256963,0.00057237,0.0004659851,0.0000163677,0.001316121,0.005539274,0.9564878,0.00009867195,0.004244053,0.01531317],"study_design_scores_gemma":[0.02200855,0.00647448,0.008045217,0.0005685614,0.001691771,0.00007001183,0.001425056,0.561579,0.319974,0.0002445918,0.07572769,0.002191004],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9723932,0.002383052,0.02337336,0.001079708,0.0001253328,0.0002304361,0.000404056,0.00000283595,0.000008087036],"genre_scores_gemma":[0.9780084,0.009186544,0.01012989,0.001843232,0.0007593402,0.00001337769,0.00001342316,0.00003320154,0.00001252822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6365138,"threshold_uncertainty_score":0.6143095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0676803290889007,"score_gpt":0.3067260043156205,"score_spread":0.2390456752267198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}