{"id":"W3040856716","doi":"10.3389/fnmol.2020.00122","title":"Zebrafish Models of LAMA2-Related Congenital Muscular Dystrophy (MDC1A)","year":2020,"lang":"en","type":"article","venue":"Frontiers in Molecular Neuroscience","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"National Institutes of Health; Genome Canada; Canadian Institutes of Health Research; Hospital for Sick Children; Natural Sciences and Engineering Research Council of Canada; Muscular Dystrophy Association","keywords":"Zebrafish; Congenital muscular dystrophy; Laminin; Muscular dystrophy; Biology; Extracellular matrix; Gene; Genetics; Neuroscience; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003732759,0.0007648512,0.0005990409,0.000975166,0.0005364653,0.0003772883,0.0006994365,0.001174064,0.00445887],"category_scores_gemma":[0.0001979398,0.0002517637,0.0005333056,0.0003040429,0.0004569767,0.0004612854,0.0004743533,0.001306836,0.001089416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001057207,"about_ca_system_score_gemma":0.0009070811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003365424,"about_ca_topic_score_gemma":0.006402841,"domain_scores_codex":[0.9997451,0.00002387609,0.00002432166,0.00005236563,0.0001179962,0.00003638226],"domain_scores_gemma":[0.9998791,0.00001767333,0.00003193849,0.00001003071,0.00002554385,0.00003572005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003188705,0.00009609594,0.0005286991,0.0007294537,0.00004167064,0.001022691,0.000117058,0.000403477,0.9651127,0.004472408,0.004544533,0.02261232],"study_design_scores_gemma":[0.0003552346,0.003276421,0.01026694,0.0005546639,0.0005646952,0.007740542,0.0002747483,0.004380843,0.7062035,0.003199526,0.2630346,0.0001482846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6376688,0.1176756,0.1380282,0.006916903,0.002741081,0.002047327,0.0203134,0.005506556,0.06910211],"genre_scores_gemma":[0.7290943,0.08581875,0.08224776,0.001698197,0.0001809067,0.00346478,0.0119377,0.0004526628,0.08510487],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00445887,"threshold_uncertainty_score":0.01491642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008074482833366693,"score_gpt":0.2053257116052019,"score_spread":0.1972512287718352,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}