{"id":"W3040856716","doi":"10.3389/fnmol.2020.00122","title":"Zebrafish Models of LAMA2-Related Congenital Muscular Dystrophy (MDC1A)","year":2020,"lang":"en","type":"article","venue":"Frontiers in Molecular Neuroscience","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"National Institutes of Health; Genome Canada; Canadian Institutes of Health Research; Hospital for Sick Children; Natural Sciences and Engineering Research Council of Canada; Muscular Dystrophy Association","keywords":"Zebrafish; Congenital muscular dystrophy; Laminin; Muscular dystrophy; Biology; Extracellular matrix; Gene; Genetics; Neuroscience; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009281142,0.0001799882,0.0002309304,0.00006593672,0.00004950166,0.00001255505,0.000500914,0.0001472083,0.000005322473],"category_scores_gemma":[0.0001479557,0.0001920126,0.0001089074,0.0003612299,0.0004303895,0.00001573139,0.0001762735,0.0001616096,0.000001762326],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005703076,"about_ca_system_score_gemma":0.00007340389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008811031,"about_ca_topic_score_gemma":0.000001037329,"domain_scores_codex":[0.998484,0.0001182517,0.0002788835,0.0006035193,0.0001999593,0.000315403],"domain_scores_gemma":[0.9994004,0.000003691695,0.00009776117,0.0003284019,0.00003893724,0.000130743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001085469,0.00006162922,0.001124411,0.00001712799,0.00001381747,0.00003330071,0.00006559148,0.01389042,0.9830006,0.0002982685,0.001103205,0.0002830477],"study_design_scores_gemma":[0.005191853,0.002749318,0.01010609,0.0000336096,0.00009495444,0.00002925108,0.0005309958,0.1349639,0.82978,0.005969177,0.008995424,0.001555427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9151034,0.0007540924,0.08226118,0.0002494082,0.0004160343,0.0002375702,0.00002728197,0.00001815644,0.000932835],"genre_scores_gemma":[0.9962929,0.0000757666,0.001924578,0.001602044,0.00001731618,0.000011068,0.00003406575,0.00002131967,0.00002094708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1532206,"threshold_uncertainty_score":0.7830046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008074482833366693,"score_gpt":0.2053257116052019,"score_spread":0.1972512287718352,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}