{"id":"W3040912026","doi":"10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2389","title":"Anti-Inflammatory/Anti-Fibrotic Compound PBI-4425 Alleviates Bleomycin- and TGF-ß1-Induced Pulmonary Fibrosis","year":2020,"lang":"en","type":"article","venue":"","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Liminal BioSciences (Canada)","funders":"","keywords":"Bleomycin; Pulmonary fibrosis; Fibrosis; Transforming growth factor; Inflammation; Medicine; Chemistry; Cancer research; Immunology; Pathology; Internal medicine; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001296138,0.0005076806,0.0006553181,0.0005156674,0.000295183,0.0001916552,0.0002642686,0.0003502646,0.003253962],"category_scores_gemma":[0.00009919131,0.0002388863,0.0003480711,0.000200461,0.0003106288,0.0002738094,0.0001852718,0.001362509,0.0005371486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001257746,"about_ca_system_score_gemma":0.0004692468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006094809,"about_ca_topic_score_gemma":0.001107501,"domain_scores_codex":[0.9998921,0.00001477744,0.00001082785,0.00001223979,0.00002629724,0.00004362813],"domain_scores_gemma":[0.9999347,0.0000050514,0.0000105654,0.000004508457,0.000005665247,0.0000394196],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003043505,0.001351368,0.0003877343,0.0003985493,0.00004186378,0.0002098486,0.00003131836,0.0003290543,0.9819043,0.0002272833,0.0007833071,0.01129184],"study_design_scores_gemma":[0.001078051,0.01165565,0.01649605,0.00005494796,0.000183808,0.0005834247,0.0001120501,0.002144298,0.9590265,0.0002160892,0.008414273,0.00003480286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869442,0.005839082,0.001664503,0.0003963272,0.0003410564,0.0001315283,0.0006232867,0.0004636488,0.00359647],"genre_scores_gemma":[0.9905589,0.003563594,0.001421789,0.0001759788,0.0000593165,0.00009313161,0.0006507711,0.00001649606,0.003460119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003253962,"threshold_uncertainty_score":0.0108856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01925873100647619,"score_gpt":0.2422454888991516,"score_spread":0.2229867578926754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}