{"id":"W3041065481","doi":"10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1245","title":"Oxidized Phosphatidylcholine Disrupts the Distribution of Caveolae and Modulates Response of Human Airway Smooth Muscle to Contractile Agonists","year":2020,"lang":"en","type":"article","venue":"","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Caveolae; Cell biology; Phosphatidylcholine; Smooth muscle; Chemistry; Distribution (mathematics); Internal medicine; Biology; Medicine; Signal transduction; Membrane; Biochemistry; Phospholipid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000150886,0.0001884944,0.0001687219,0.0001874756,0.0002190033,0.0003509809,0.0002623336,0.0003804998,0.0014511],"category_scores_gemma":[0.0003047815,0.0002574128,0.0002385233,0.0002105393,0.0003322987,0.0002350264,0.0002291702,0.000586383,0.0001708987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003753271,"about_ca_system_score_gemma":0.0002701939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002855505,"about_ca_topic_score_gemma":0.002784862,"domain_scores_codex":[0.9998472,0.00003049495,0.00001297804,0.00001947151,0.00002463259,0.00006522555],"domain_scores_gemma":[0.9998738,0.0000441418,0.00002085759,0.00001793264,0.00001223109,0.00003102131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001286738,0.00005535451,0.000328938,0.00002365324,0.00001363492,0.0001326879,0.00003556266,0.00005749436,0.9973074,0.0001330662,0.0000310141,0.0005943511],"study_design_scores_gemma":[0.00009096078,0.0005974389,0.01770655,0.000007709151,0.00004480299,0.0004250898,0.0001169599,0.00101797,0.978972,0.00009396928,0.0009186223,0.000008116994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990284,0.0003114738,0.0002322959,0.00005178305,0.0000108439,0.000004959943,0.00006294834,0.000005983335,0.0002912834],"genre_scores_gemma":[0.9986084,0.0002114483,0.0001812896,0.00003106351,0.000004667053,0.00000626267,0.0001300762,0.000005730706,0.0008209926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002855505,"threshold_uncertainty_score":0.0056777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009935158712162506,"score_gpt":0.2515301131105285,"score_spread":0.241594954398366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}