{"id":"W3041166253","doi":"10.1097/ta.0000000000002868","title":"Impact of uric acid on liver injury and intestinal permeability following resuscitated hemorrhagic shock in rats","year":2020,"lang":"en","type":"article","venue":"The Journal of Trauma: Injury, Infection, and Critical Care","topic":"Gout, Hyperuricemia, Uric Acid","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Université de Montréal; Sanofi Genzyme; Sanofi","keywords":"Rasburicase; Urate oxidase; Uric acid; Medicine; Liver injury; Proinflammatory cytokine; Resuscitation; Pharmacology; Internal medicine; Inflammation; Surgery; Hyperuricemia","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003648736,0.0008461613,0.0007231951,0.000807282,0.0003020594,0.0003447829,0.0003384541,0.000512626,0.001853022],"category_scores_gemma":[0.0002399608,0.0003451119,0.0005817492,0.0002869558,0.0006268546,0.0006168904,0.0003197683,0.001347022,0.0002970177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000456561,"about_ca_system_score_gemma":0.0005012099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008969188,"about_ca_topic_score_gemma":0.001164327,"domain_scores_codex":[0.9997836,0.00003419268,0.00001894846,0.00003701775,0.00004337155,0.00008285002],"domain_scores_gemma":[0.9996101,0.00002221183,0.0001328491,0.00003830046,0.00004345809,0.000153072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0137531,0.002678598,0.002478698,0.0002516622,0.0000744842,0.0005536696,0.0002254698,0.0003565539,0.9719596,0.0002613628,0.0002466779,0.007160057],"study_design_scores_gemma":[0.0003837797,0.03030516,0.0169851,0.00003556696,0.0001747528,0.0004681585,0.0003671204,0.001722686,0.9477092,0.0002148881,0.001592779,0.00004079553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967129,0.001327258,0.0008481759,0.0001538006,0.00007733125,0.00004724339,0.0001898185,0.00006627214,0.0005772699],"genre_scores_gemma":[0.9956383,0.001077524,0.0009856207,0.00009454503,0.00002935585,0.00008758198,0.0002919085,0.00001096609,0.00178423],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001853022,"threshold_uncertainty_score":0.006198943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0261610362143433,"score_gpt":0.3281848891114557,"score_spread":0.3020238528971124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}