{"id":"W3041227011","doi":"10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6204","title":"A Safe and Novel Biophysical Mucus Expectorant for Cystic Fibrosis and Non-CF Bronchiectasis: Preliminary Results from a Phase IIa Trial","year":2020,"lang":"en","type":"article","venue":"","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Health Services; University of Calgary","funders":"","keywords":"Expectorant; Bronchiectasis; Cystic fibrosis; Mucus; Medicine; Field trial; Pathology; Internal medicine; Lung; Pharmacology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001126742,0.0006867042,0.001553324,0.0002155762,0.0002566181,0.001096602,0.0004959248,0.00146996,0.003572016],"category_scores_gemma":[0.0008929915,0.0001960927,0.001592909,0.0002007424,0.0007061418,0.0009369088,0.0003382413,0.003144203,0.0005853582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000476492,"about_ca_system_score_gemma":0.0006498648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005865425,"about_ca_topic_score_gemma":0.001706221,"domain_scores_codex":[0.9997399,0.0001017497,0.0000144107,0.00003350613,0.00003704824,0.00007332593],"domain_scores_gemma":[0.9995785,0.0001226582,0.00006125073,0.00002545777,0.00002262875,0.0001894184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.484331,0.02242803,0.005678306,0.004285973,0.003276216,0.001320575,0.0005829948,0.002860369,0.06711432,0.001617563,0.01334087,0.3931638],"study_design_scores_gemma":[0.5876666,0.3668862,0.01579127,0.0004251475,0.001507986,0.001032522,0.0002832439,0.001738434,0.005434099,0.001114122,0.01804547,0.00007486493],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9446862,0.0431969,0.001880716,0.003589334,0.0007852435,0.001404816,0.001116339,0.0002088326,0.00313159],"genre_scores_gemma":[0.9767252,0.01226554,0.002413857,0.003065676,0.0003793887,0.0008856691,0.001541573,0.00003867664,0.002684557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003572016,"threshold_uncertainty_score":0.0119496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03698833406441281,"score_gpt":0.3318389002306168,"score_spread":0.294850566166204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}