{"id":"W3041244286","doi":"10.1016/j.jcmgh.2020.07.003","title":"Muc2 Mucin and Nonmucin Microbiota Confer Distinct Innate Host Defense in Disease Susceptibility and Colonic Injury","year":2020,"lang":"en","type":"article","venue":"Cellular and Molecular Gastroenterology and Hepatology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre; Health Sciences Centre; University of Calgary","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Canada","keywords":"Mucin; Innate immune system; Immunology; Host (biology); Disease; Biology; Medicine; Immune system; Pathology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003880397,0.0003483858,0.0002716773,0.000354142,0.0001530493,0.0003948347,0.0001751615,0.0004415664,0.001280581],"category_scores_gemma":[0.000210242,0.0001639664,0.0002420495,0.0001569907,0.0004314164,0.000284813,0.0004540592,0.0005167846,0.0001248119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003109919,"about_ca_system_score_gemma":0.0003056629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003267347,"about_ca_topic_score_gemma":0.0005971418,"domain_scores_codex":[0.9997517,0.00006889361,0.00001825812,0.0000476554,0.00004341437,0.00007012102],"domain_scores_gemma":[0.9997092,0.00001634675,0.00008256291,0.00002828241,0.00001633183,0.00014727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007742659,0.00004256106,0.003326677,0.00002984628,0.000007363516,0.0001040845,0.00002340495,0.00001976975,0.9945548,0.0001494281,0.00001406165,0.0009537094],"study_design_scores_gemma":[0.00008040517,0.003135509,0.3419792,0.0000367632,0.00008523701,0.002984029,0.0003709754,0.001030888,0.648009,0.0003342416,0.001937027,0.000016698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984237,0.0006157777,0.000475766,0.00004383799,0.000005136305,0.00000635392,0.00004413268,0.00001190756,0.0003735283],"genre_scores_gemma":[0.9985943,0.0001823512,0.0006068571,0.00002561537,0.000005207731,0.0000114987,0.00007515131,0.000003946007,0.0004949332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001280581,"threshold_uncertainty_score":0.004283965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008428552278979231,"score_gpt":0.2340068599276441,"score_spread":0.2255783076486649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}