{"id":"W3041244286","doi":"10.1016/j.jcmgh.2020.07.003","title":"Muc2 Mucin and Nonmucin Microbiota Confer Distinct Innate Host Defense in Disease Susceptibility and Colonic Injury","year":2020,"lang":"en","type":"article","venue":"Cellular and Molecular Gastroenterology and Hepatology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre; Health Sciences Centre; University of Calgary","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Canada","keywords":"Mucin; Innate immune system; Immunology; Host (biology); Disease; Biology; Medicine; Immune system; Pathology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001987401,0.0002485676,0.0003422084,0.00008400447,0.0001010581,0.00002978892,0.00009264239,0.0002334523,0.00002186822],"category_scores_gemma":[0.0001276788,0.0002506626,0.00004431182,0.00006082957,0.00068409,0.000007974815,0.0003944777,0.0002645805,0.000002253156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007549698,"about_ca_system_score_gemma":0.00005029962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005404491,"about_ca_topic_score_gemma":0.0003909821,"domain_scores_codex":[0.9981295,0.000328973,0.0002755759,0.0007652391,0.0000645999,0.0004361222],"domain_scores_gemma":[0.9992583,0.00001585412,0.00006239776,0.0002214319,0.00005087411,0.000391165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001603553,0.00005535251,0.4839118,0.00009450408,0.00003603798,0.0001714145,0.0001023713,5.264907e-7,0.5135148,0.0001526973,0.00007187766,0.0002850948],"study_design_scores_gemma":[0.0145372,0.007366359,0.8157547,0.00007049056,0.0002403938,0.0006602485,0.0002783543,0.003493462,0.1280111,0.0005642732,0.0278009,0.001222506],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936829,0.002246995,0.0007501578,0.002804427,0.00003284932,0.0003928998,0.00005499521,0.00001046805,0.00002433772],"genre_scores_gemma":[0.9965159,0.0007101985,0.000117165,0.002445519,0.00002371753,0.00002587236,0.000120449,0.00002041993,0.00002070913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3855036,"threshold_uncertainty_score":0.9999946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008428552278979231,"score_gpt":0.2340068599276441,"score_spread":0.2255783076486649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}