{"id":"W3041383339","doi":"10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4049","title":"Gene Expression Profiling in Patients with Idiopathic Pulmonary Fibrosis (IPF) Treated with Nintedanib and Sildenafil: Data from the INSTAGE Trial","year":2020,"lang":"en","type":"article","venue":"","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"","keywords":"Nintedanib; Sildenafil; Idiopathic pulmonary fibrosis; Medicine; Gene expression profiling; Profiling (computer programming); Gene expression; Internal medicine; Bioinformatics; Gene; Biology; Lung; Genetics; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001355563,0.0006388157,0.002250056,0.0002958649,0.0003074082,0.00104565,0.0003856744,0.0009577779,0.001147711],"category_scores_gemma":[0.001388434,0.0002408692,0.00120745,0.000729771,0.0004970758,0.0005329672,0.0002877992,0.0009286507,0.0002476764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004194036,"about_ca_system_score_gemma":0.0004166075,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005520686,"about_ca_topic_score_gemma":0.001006039,"domain_scores_codex":[0.9991621,0.0003956015,0.00006041532,0.0001501331,0.0001265364,0.0001053075],"domain_scores_gemma":[0.999089,0.0003394186,0.000227939,0.00007834298,0.00007405038,0.00019115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.489961,0.002828001,0.435946,0.0004943831,0.004507686,0.0003290746,0.0002009229,0.0007592308,0.02131293,0.0002224935,0.002783255,0.04065503],"study_design_scores_gemma":[0.03277937,0.02327874,0.9338543,0.00005257776,0.003367063,0.0004064265,0.0001939147,0.001010685,0.002016199,0.000318423,0.002665337,0.00005688016],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952646,0.002688648,0.0001062259,0.0001857586,0.00005592029,0.00004322529,0.0009536582,0.000009391005,0.0006926518],"genre_scores_gemma":[0.9944384,0.001017883,0.0003204769,0.0004032302,0.0001806013,0.0001454525,0.003029844,0.000007443407,0.0004566713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002250056,"threshold_uncertainty_score":0.007168949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02557788176779329,"score_gpt":0.2402607548896926,"score_spread":0.2146828731218993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}