{"id":"W3041457641","doi":"10.1016/j.annonc.2020.04.220","title":"P-138 A comparison of the transcriptomic profiles of matched tissue from primary colorectal cancer and corresponding secondary lung metastases","year":2020,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Cancer Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill Genome Centre","funders":"","keywords":"Medicine; Metastasectomy; Colorectal cancer; Rectum; Lung; Transcriptome; Metastasis; Lung cancer; Oncology; Primary tumor; KRAS; Pathology; Cancer; Internal medicine; Gene; Gene expression; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008818295,0.0001069833,0.0008092221,0.00003995902,0.00002124728,0.000001911554,0.00007366556,0.00007137948,0.0002916649],"category_scores_gemma":[0.00004323337,0.00007531244,0.0001022219,0.0001186859,0.0001918434,0.00003162391,0.00004318288,0.0001103254,4.937166e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003781326,"about_ca_system_score_gemma":0.0003639754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001073456,"about_ca_topic_score_gemma":0.0002832159,"domain_scores_codex":[0.9991091,0.00008126959,0.0003890468,0.0001722371,0.0001297106,0.0001186243],"domain_scores_gemma":[0.9991383,0.000318973,0.0002911925,0.0001003268,0.00008302761,0.00006819735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004670688,0.001159075,0.3806664,0.0008945347,0.001357562,0.00002314969,0.009838387,0.00001922021,0.4768938,0.0001130379,0.02806268,0.09630141],"study_design_scores_gemma":[0.002136702,0.002184295,0.3011264,0.0001673061,0.0004680392,0.000003945489,0.000583226,0.00007594028,0.6857303,0.00002060889,0.007445859,0.0000574337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9744341,0.0139596,0.000005652571,0.009896968,0.00012288,0.0004807453,0.0006825032,0.000006813457,0.0004107411],"genre_scores_gemma":[0.9976559,0.0008367274,0.0002497646,0.00109604,0.00004765392,0.00005112477,0.00003711275,0.00001068557,0.00001496041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2088364,"threshold_uncertainty_score":0.3193526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07437366104296167,"score_gpt":0.3892277187350009,"score_spread":0.3148540576920393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}