{"id":"W3041522589","doi":"10.3390/cells9071672","title":"MRIP Regulates the Myosin IIA Activity and DDR1 Function to Enable Collagen Tractional Remodeling","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"DDR1; Cell biology; Myosin; Collagen receptor; Chemistry; Integrin; Biology; Signal transduction; Cell; Biochemistry; Receptor tyrosine kinase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001603217,0.0004948298,0.0002894944,0.0002415378,0.0001985597,0.0003053283,0.0003229986,0.0003492045,0.001104066],"category_scores_gemma":[0.0001277772,0.0002237869,0.0002481792,0.0001215624,0.0003395328,0.0002156338,0.0003140446,0.0004903963,0.0004673116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004199276,"about_ca_system_score_gemma":0.0001984215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002786878,"about_ca_topic_score_gemma":0.0004725008,"domain_scores_codex":[0.9998325,0.00002212724,0.00001328838,0.00004747702,0.00004866162,0.00003597759],"domain_scores_gemma":[0.9998958,0.00001493493,0.00004578537,0.00001134689,0.000006994353,0.00002509353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001441119,0.000004660438,0.00007837357,0.00001112571,7.892545e-7,0.00003535512,0.000003039027,0.00002578083,0.9993865,0.00008579255,0.00001149233,0.0003425192],"study_design_scores_gemma":[0.000007147544,0.00003614123,0.003411848,0.000003651639,0.000004963047,0.0003696622,0.00001327812,0.0009216709,0.9935132,0.00004383854,0.001671667,0.000003078187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869778,0.002020918,0.007886662,0.0002331358,0.00003152705,0.00002646886,0.0003755557,0.0001645779,0.002283349],"genre_scores_gemma":[0.993288,0.0006792669,0.003460551,0.00005042309,0.000008574373,0.00002585691,0.0003202647,0.00004326237,0.002123905],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001104066,"threshold_uncertainty_score":0.003693461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01427738844013427,"score_gpt":0.2151977836325948,"score_spread":0.2009203951924606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}