{"id":"W3041522589","doi":"10.3390/cells9071672","title":"MRIP Regulates the Myosin IIA Activity and DDR1 Function to Enable Collagen Tractional Remodeling","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"DDR1; Cell biology; Myosin; Collagen receptor; Chemistry; Integrin; Biology; Signal transduction; Cell; Biochemistry; Receptor tyrosine kinase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009282052,0.00008625994,0.00006922406,0.00001350525,0.0001569294,0.00004629419,0.00006922495,0.00006925791,0.0000932347],"category_scores_gemma":[0.00002820396,0.00007172542,0.00004806759,0.0000726939,0.000013507,0.000006203919,0.00006993176,0.00006282198,0.00002905636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001002917,"about_ca_system_score_gemma":0.00002920268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002394251,"about_ca_topic_score_gemma":0.00001480715,"domain_scores_codex":[0.9994427,0.00003040588,0.00008805435,0.0002443577,0.00007446131,0.0001200217],"domain_scores_gemma":[0.9996662,0.00001234944,0.00003685214,0.0001469688,0.00004975436,0.0000878463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000884414,0.00001610048,0.000004581349,0.000004891554,0.00002033717,3.82584e-7,0.00005234765,0.0006415712,0.98803,0.00005136215,0.009685983,0.001403981],"study_design_scores_gemma":[0.0001016875,0.0001273536,0.00007405611,0.000003094711,0.00001719093,0.000003894782,0.00007624696,0.005250437,0.7467303,0.00007719863,0.2474596,0.00007897499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807381,0.0002809974,0.0143818,0.002672904,0.0003324708,0.0001947417,0.00001409015,0.00001302011,0.001371876],"genre_scores_gemma":[0.9964617,0.00008386404,0.0002367967,0.001118331,0.0003388012,0.00001342971,0.00002102385,0.00001307929,0.001712913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2412997,"threshold_uncertainty_score":0.2924878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01427738844013427,"score_gpt":0.2151977836325948,"score_spread":0.2009203951924606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}