{"id":"W3041582921","doi":"10.1111/trf.15932","title":"Daudi cell stroma: An alternative to dithiothreitol to resolve daratumumab interference in pretransfusion testing","year":2020,"lang":"en","type":"article","venue":"Transfusion","topic":"Blood groups and transfusion","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Canadian Blood Services; Héma-Québec","funders":"","keywords":"Daratumumab; Dithiothreitol; Stroma; Molecular biology; Chemistry; Antigen; Trypsinization; Flow cytometry; Andrology; Immunology; Medicine; Antibody; Trypsin; Biology; Biochemistry; Monoclonal antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002392409,0.0003801088,0.0005556984,0.0002583953,0.0001565906,0.00004574407,0.0002942442,0.0001788114,0.0001623618],"category_scores_gemma":[0.00008646474,0.0003432844,0.0001018658,0.001190891,0.00003493051,0.0002504228,0.00006079002,0.0006926309,0.00008988271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008577312,"about_ca_system_score_gemma":0.00008524479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001004221,"about_ca_topic_score_gemma":0.0009353776,"domain_scores_codex":[0.9972983,0.000104473,0.0005571393,0.001010038,0.0005070739,0.000522989],"domain_scores_gemma":[0.9984466,0.0000893384,0.00004434656,0.0004054813,0.0001531005,0.0008610861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002958938,0.0006986126,0.01957332,0.0002431907,0.00001516427,0.0002475342,0.01885901,0.0005138135,0.9289246,0.00004597736,0.00008199755,0.02783782],"study_design_scores_gemma":[0.01794317,0.03299082,0.2361243,0.003380391,0.0003388638,0.00007918248,0.002716951,0.01603094,0.6868124,0.000137166,0.001686354,0.001759475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9545138,0.00006102797,0.03459247,0.003848154,0.0002285686,0.001897975,0.00002963705,0.0001804194,0.004647869],"genre_scores_gemma":[0.98615,0.00005750978,0.01153915,0.001736922,0.0003080558,0.00006150504,0.00002943199,0.00006861133,0.00004883011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2421122,"threshold_uncertainty_score":0.9999019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04614452117146877,"score_gpt":0.2858503910952885,"score_spread":0.2397058699238198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}