{"id":"W3041588796","doi":"10.1111/his.14205","title":"Gene fusion characterisation of rare aggressive prostate cancer variants—adenosquamous carcinoma, pleomorphic giant‐cell carcinoma, and sarcomatoid carcinoma: an analysis of 19 cases","year":2020,"lang":"en","type":"article","venue":"Histopathology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Memorial University of Newfoundland","funders":"Henry Ford Health System","keywords":"Adenosquamous carcinoma; Fusion gene; Sarcomatoid carcinoma; Erg; Carcinoma; Adenocarcinoma; Immunohistochemistry; Pathology; Biology; TMPRSS2; Gene rearrangement; Cancer; Cancer research; Medicine; Gene; Genetics; Retina","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001698131,0.0002938806,0.001052631,0.0005329404,0.0001322898,0.000009060971,0.0001448027,0.0001863721,0.0002328986],"category_scores_gemma":[0.000096717,0.0002526066,0.0001619917,0.0006960677,0.000407192,0.0001200632,0.0001218937,0.0002326578,0.000003331751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002144837,"about_ca_system_score_gemma":0.0004637876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002402217,"about_ca_topic_score_gemma":0.0001668665,"domain_scores_codex":[0.9977424,0.0002612182,0.0005906138,0.0006689617,0.0003410886,0.0003957472],"domain_scores_gemma":[0.9981421,0.00007932654,0.0006281661,0.0004432724,0.0003374499,0.0003696544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001473894,0.0002108984,0.6247512,0.0004659009,0.00004582268,0.003405813,0.008074686,0.0000131455,0.3607395,0.000006887171,0.00007814538,0.0007340884],"study_design_scores_gemma":[0.003318896,0.001818689,0.9422678,0.00002930904,0.001522698,0.0003715529,0.0007549973,0.001780902,0.04786351,0.000004487315,0.00006259026,0.0002045248],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9762219,0.02100174,0.00002266056,0.0009189873,0.0001030727,0.000746652,0.0008961572,0.00002965369,0.00005918264],"genre_scores_gemma":[0.9973558,0.0008708884,0.0001999456,0.0002206174,0.00008037703,0.00008217541,0.0009081925,0.00003860228,0.0002434656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3175167,"threshold_uncertainty_score":0.9999926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03315604599383103,"score_gpt":0.282988456430602,"score_spread":0.249832410436771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}