{"id":"W3041695571","doi":"10.3390/genes11070765","title":"Cardiac Involvement in Dystrophin-Deficient Females: Current Understanding and Implications for the Treatment of Dystrophinopathies","year":2020,"lang":"en","type":"review","venue":"Genes","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; Muscular Dystrophy Canada; Canadian Institutes of Health Research; Alberta Innovates; Women and Children's Health Research Institute","keywords":"Dystrophin; Duchenne muscular dystrophy; Medicine; Muscular dystrophy; Dilated cardiomyopathy; Heart failure; Cardiomyopathy; Respiratory failure; Bioinformatics; Mutation; Internal medicine; Cardiology; Genetics; Gene; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004868147,0.0006651791,0.001061265,0.001609919,0.000200307,0.0007182721,0.0007326974,0.0009702033,0.002912835],"category_scores_gemma":[0.0008802275,0.0001627468,0.0003879956,0.001436199,0.0003972487,0.000943621,0.0005214399,0.001665217,0.001542937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003663776,"about_ca_system_score_gemma":0.0005473444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005893938,"about_ca_topic_score_gemma":0.001019264,"domain_scores_codex":[0.9998447,0.00003081857,0.00002685333,0.00003094852,0.00005256694,0.00001418748],"domain_scores_gemma":[0.9996552,0.0002007094,0.00003878807,0.00000809054,0.00006534973,0.00003194785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007568268,0.00005902397,0.0001689154,0.01114013,0.00005328569,0.0003048453,0.00004921906,0.0002319037,0.001090263,0.002080658,0.0229297,0.9618163],"study_design_scores_gemma":[0.00003006161,0.0001281723,0.001410956,0.007195537,0.0001662252,0.003886887,0.00007305122,0.0001029393,0.0004091174,0.002333602,0.9842426,0.00002080848],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007267001,0.9991033,0.00006894616,0.0002172946,0.0001129593,0.000001218624,0.00000737791,0.000004680074,0.0004115582],"genre_scores_gemma":[0.0004186307,0.9989421,0.0001048807,0.0001570452,0.000134822,0.000002714543,0.00001524324,0.000001293717,0.000223266],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002912835,"threshold_uncertainty_score":0.009744465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1315942584026202,"score_gpt":0.3555313660393183,"score_spread":0.2239371076366981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}