{"id":"W3041695571","doi":"10.3390/genes11070765","title":"Cardiac Involvement in Dystrophin-Deficient Females: Current Understanding and Implications for the Treatment of Dystrophinopathies","year":2020,"lang":"en","type":"review","venue":"Genes","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; Muscular Dystrophy Canada; Canadian Institutes of Health Research; Alberta Innovates; Women and Children's Health Research Institute","keywords":"Dystrophin; Duchenne muscular dystrophy; Medicine; Muscular dystrophy; Dilated cardiomyopathy; Heart failure; Cardiomyopathy; Respiratory failure; Bioinformatics; Mutation; Internal medicine; Cardiology; Genetics; Gene; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000624283,0.0002165697,0.0005358377,0.00004369536,0.00009301791,0.000009259866,0.0001215983,0.0001043182,7.135944e-7],"category_scores_gemma":[0.00001120858,0.0001399848,0.0002659054,0.00007759513,0.0001172669,0.000001072943,0.00005272816,0.00004063516,4.488534e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005383117,"about_ca_system_score_gemma":0.0001227487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009782601,"about_ca_topic_score_gemma":0.00001953982,"domain_scores_codex":[0.9991381,0.00005879791,0.0002798793,0.0003304842,0.00003855065,0.0001541603],"domain_scores_gemma":[0.9994681,0.0000607681,0.0001494131,0.0002678382,0.00001966832,0.00003415647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003834359,0.0001619776,0.0002429575,0.003583386,0.0003173248,2.362113e-7,0.0001796088,0.00002382146,0.0008041386,0.001946188,0.0001203081,0.9925817],"study_design_scores_gemma":[0.0002325315,0.0005092454,0.0001512819,0.000267693,0.0003559227,9.779224e-7,0.0002867433,0.000003738309,0.00006901912,0.000233328,0.9977289,0.0001605759],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001706094,0.9960662,0.0006875276,0.00008345782,0.0001622535,0.001030189,0.0002521552,0.000003936451,0.000008171544],"genre_scores_gemma":[0.005054549,0.9938434,0.00004616078,0.000006597234,0.0001271316,0.0006088609,0.0002904484,0.00001682107,0.000006080643],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9976087,"threshold_uncertainty_score":0.5708416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1315942584026202,"score_gpt":0.3555313660393183,"score_spread":0.2239371076366981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}