{"id":"W3041726272","doi":"","title":"Inhibition of MLK3 decreases proliferation and increases antiproliferative activity of epidermal growth factor receptor (EGFR) inhibitor in pancreatic cancer cell lines","year":2008,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cancer research; MAPK/ERK pathway; Protein kinase B; Kinase; Cell growth; KRAS; Biology; Cell culture; Signal transduction; Cancer; Cell biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001665138,0.0005381702,0.0003350459,0.000378366,0.0002322493,0.0003343286,0.0002872024,0.0002527278,0.003462102],"category_scores_gemma":[0.0001193121,0.0001512769,0.0003723273,0.0004543976,0.0002410376,0.0002118118,0.0001723302,0.0008500103,0.0008248551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003878252,"about_ca_system_score_gemma":0.000388958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005294547,"about_ca_topic_score_gemma":0.000904171,"domain_scores_codex":[0.9997448,0.00002913615,0.00003516905,0.00004046524,0.0001045683,0.00004584726],"domain_scores_gemma":[0.999916,0.00001767122,0.00002379506,0.0000100791,0.00001128956,0.00002117287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004851386,0.0003062013,0.0005609129,0.0002237051,0.00001345209,0.0001115867,0.00001973694,0.0001215605,0.9946499,0.00008655408,0.0004958723,0.002925329],"study_design_scores_gemma":[0.00007459081,0.00102157,0.005364204,0.00001414719,0.0000327569,0.0003943175,0.00002268463,0.000659142,0.9883252,0.00002857933,0.00405694,0.000005924823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793901,0.006385107,0.003988053,0.0004446167,0.0001597068,0.0001786152,0.003080234,0.0004123791,0.005961111],"genre_scores_gemma":[0.9793312,0.004909785,0.00581325,0.000187743,0.00004514666,0.0003512749,0.004313748,0.00004915686,0.004998643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003462102,"threshold_uncertainty_score":0.0115819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1458144996345921,"score_gpt":0.4727596900669184,"score_spread":0.3269451904323264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}