{"id":"W3041763021","doi":"10.1001/jamacardio.2020.2497","title":"Natural History of Asymptomatic Severe Aortic Stenosis and the Association of Early Intervention With Outcomes","year":2020,"lang":"en","type":"review","venue":"JAMA Cardiology","topic":"Cardiac Valve Diseases and Treatments","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital; Université Laval","funders":"St. Jude Medical; Medicines Company; Boston Scientific Corporation; Eli Lilly and Company; Edwards Lifesciences; AstraZeneca","keywords":"Medicine; Natural history; Asymptomatic; Stenosis; Internal medicine; Intervention (counseling); Aortic valve stenosis; Cardiology; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01699711,0.001112601,0.00618307,0.00170489,0.0002875951,0.002698408,0.001239195,0.002043758,0.001319567],"category_scores_gemma":[0.03811046,0.0007151973,0.01782019,0.002129057,0.0007273178,0.001409107,0.0007285067,0.001720836,0.0001246165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009435729,"about_ca_system_score_gemma":0.001316442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00236004,"about_ca_topic_score_gemma":0.004479702,"domain_scores_codex":[0.9901059,0.006012599,0.001692786,0.001074152,0.000911433,0.0002030945],"domain_scores_gemma":[0.9565334,0.03442633,0.006463001,0.001280841,0.001002596,0.0002937161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"systematic_review","study_design_scores_codex":[0.007145851,0.00006181439,0.05751972,0.1621126,0.7305694,0.0001775409,0.0001271277,0.001706149,0.0004470063,0.0006413394,0.001432869,0.03805861],"study_design_scores_gemma":[0.001539219,0.0009264977,0.05327582,0.03155548,0.9045779,0.0003687674,0.000102103,0.001039777,0.0003259781,0.001922301,0.004298072,0.00006801821],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01340465,0.9839617,0.0007303348,0.0008400283,0.0002446084,0.00004937832,0.00032114,0.0000158252,0.0004324368],"genre_scores_gemma":[0.6356306,0.3560939,0.003624699,0.002044332,0.0011917,0.0002661899,0.0007703711,0.00002635652,0.0003517189],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01699711,"threshold_uncertainty_score":0.08989042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01447235353119243,"score_gpt":0.3125525299699621,"score_spread":0.2980801764387697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}