{"id":"W3041967785","doi":"10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4414","title":"Differential Methylation of TWIST1 Is a Biomarker of Airway Versus Parenchymal Fibroblasts Within the Lung: Relevance to Asthma Pathogenesis","year":2020,"lang":"en","type":"article","venue":"","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Paul's Hospital; McMaster University; University of British Columbia","funders":"","keywords":"Pathogenesis; Asthma; Biomarker; Parenchyma; Airway; Methylation; Medicine; Clinical significance; Lung; Pathology; Differential diagnosis; Relevance (law); Immunology; Biology; Internal medicine; Gene; Genetics; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003298246,0.0002073743,0.0003022383,0.0006188948,0.000277528,0.0005159075,0.0002266962,0.0003219057,0.001931872],"category_scores_gemma":[0.0007350532,0.0001899047,0.0002117795,0.0004287029,0.0003039478,0.0002982873,0.0002776223,0.0004299425,0.0002919078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002215729,"about_ca_system_score_gemma":0.0001658331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001363709,"about_ca_topic_score_gemma":0.002157766,"domain_scores_codex":[0.9996935,0.0000604104,0.00002037456,0.00008493889,0.00007073004,0.00007004242],"domain_scores_gemma":[0.9995629,0.00008229348,0.0001873204,0.00003165709,0.00006371483,0.00007208477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001596674,0.00003232358,0.2869322,0.0002281222,0.0002111337,0.0003781863,0.0003141564,0.00022004,0.6963847,0.000336734,0.0002466667,0.01311912],"study_design_scores_gemma":[0.00002090679,0.0003035663,0.9002134,0.00003657451,0.0001500153,0.002087209,0.0005279242,0.0009454116,0.09334242,0.0005263177,0.001821893,0.00002446659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944707,0.002145565,0.001514006,0.0001014772,0.00002142642,0.00001025427,0.0008073389,0.00002361534,0.000905569],"genre_scores_gemma":[0.9984475,0.0003392017,0.0004671859,0.00002920229,0.00001228584,0.000007629105,0.000267908,0.000006688376,0.0004224621],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001931872,"threshold_uncertainty_score":0.006462753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07041767362159058,"score_gpt":0.3659245617874605,"score_spread":0.29550688816587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}