{"id":"W3041971789","doi":"10.1111/sji.12929","title":"Metabolic optimization of adoptive T cell transfer cancer immunotherapy: A historical overview","year":2020,"lang":"en","type":"article","venue":"Scandinavian Journal of Immunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Adoptive cell transfer; Cytotoxic T cell; Immunotherapy; Cancer immunotherapy; Cancer research; Biology; CD8; T cell; Immunology; Cell biology; Antigen; Biochemistry; In vitro; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001323089,0.0009921442,0.0008110366,0.00203557,0.0003720038,0.002231826,0.0008767646,0.001307211,0.001963423],"category_scores_gemma":[0.0008637873,0.0005018744,0.0006489315,0.002400406,0.001112408,0.001986846,0.001104574,0.002214852,0.001109382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001534011,"about_ca_system_score_gemma":0.0007262445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009272824,"about_ca_topic_score_gemma":0.0006118317,"domain_scores_codex":[0.9995655,0.0001104822,0.00004843378,0.0001077166,0.000125323,0.00004253029],"domain_scores_gemma":[0.9995444,0.0002041504,0.00006230483,0.00003019815,0.0001227863,0.00003615548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003504248,0.0005635315,0.00132039,0.01194752,0.0001460107,0.0005442415,0.0002940325,0.00826068,0.01859078,0.06742132,0.01270633,0.8778548],"study_design_scores_gemma":[0.00003033009,0.001038346,0.001835849,0.002556515,0.0001140627,0.001261752,0.0001852144,0.003135891,0.01733488,0.01774033,0.9546688,0.00009810095],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002694387,0.9824657,0.00606364,0.0008769979,0.0003592976,0.00002539136,0.00004726092,0.0000302141,0.007437075],"genre_scores_gemma":[0.01640419,0.9741886,0.006029482,0.0006589724,0.0006707223,0.00005805505,0.00007688933,0.00003005017,0.001883081],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002231826,"threshold_uncertainty_score":0.01113009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04227273855186823,"score_gpt":0.3049493309169022,"score_spread":0.262676592365034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}