{"id":"W3042038107","doi":"10.3390/cells9071658","title":"Identifying the Structural Adaptations that Drive the Mechanical Load-Induced Growth of Skeletal Muscle: A Scoping Review","year":2020,"lang":"en","type":"review","venue":"Cells","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":156,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Myofibril; Muscle hypertrophy; Myocyte; Skeletal muscle; Mechanical load; Ultrastructure; Cell biology; Sarcomere; Sarcopenia; Anatomy; Biology; Chemistry; Biophysics; Materials science; Endocrinology; Composite material","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001073265,0.0009584324,0.001770436,0.005313737,0.0004152035,0.001718596,0.001202781,0.001375509,0.006111321],"category_scores_gemma":[0.00341207,0.0003928267,0.001359835,0.005476139,0.0005174564,0.0017176,0.0009830943,0.001394051,0.002047942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001020133,"about_ca_system_score_gemma":0.003436371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002505275,"about_ca_topic_score_gemma":0.004501642,"domain_scores_codex":[0.9996251,0.00006213457,0.00009118344,0.00006122531,0.0001299719,0.00003036204],"domain_scores_gemma":[0.998257,0.001161762,0.0001964671,0.00003552842,0.0002899232,0.00005931749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00006687572,0.00003922631,0.0002360385,0.1685838,0.000333747,0.0002380745,0.0001843431,0.0003763946,0.001328586,0.003573358,0.03470198,0.7903376],"study_design_scores_gemma":[0.00001465764,0.00007381528,0.001621276,0.09977698,0.0009121177,0.001119603,0.0001852489,0.0000959792,0.0005038191,0.002778709,0.8928816,0.00003621355],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007943905,0.9986628,0.0001098476,0.0002733228,0.0001697768,0.000007907552,0.00004960154,0.000008226514,0.0006391438],"genre_scores_gemma":[0.0002878535,0.999087,0.0001401003,0.0001278413,0.00005827671,0.000009292263,0.00004888231,0.00000174807,0.0002390865],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006111321,"threshold_uncertainty_score":0.02044439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05841272286901542,"score_gpt":0.3394874716368683,"score_spread":0.2810747487678529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}