{"id":"W3042054217","doi":"10.3390/proceedings2020050129","title":"Visualizing HCV Core Protein via Fluorescent Unnatural Amino Acid Incorporation","year":2020,"lang":"en","type":"article","venue":"","topic":"Hepatitis C virus research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Memorial University of Newfoundland","funders":"","keywords":"Amino acid; Green fluorescent protein; Protein biosynthesis; Protein engineering; Transfer RNA; Biology; Biochemistry; Genetic code; Transfection; Fusion protein; Cell-free protein synthesis; Chemistry; Molecular biology; Gene; RNA; Enzyme; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001798997,0.0002860768,0.0001347836,0.0001985422,0.0001349919,0.0002155372,0.000189484,0.0003102491,0.0005210581],"category_scores_gemma":[0.0001070856,0.000125415,0.0001876419,0.0001492014,0.0001891795,0.0001818854,0.0002332181,0.0003225214,0.0002376584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003601117,"about_ca_system_score_gemma":0.0002207179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006579624,"about_ca_topic_score_gemma":0.0008308138,"domain_scores_codex":[0.9998839,0.00002215526,0.00000800127,0.0000269716,0.00003725913,0.00002168705],"domain_scores_gemma":[0.9999102,0.00002168628,0.00002421532,0.00001243345,0.00001785577,0.00001353438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001793171,0.00000468714,0.00005896107,0.00002025888,0.00000150232,0.00001913804,0.000005946163,0.00003911073,0.999185,0.00008057793,0.00001487638,0.0005518704],"study_design_scores_gemma":[0.000003570176,0.00004357374,0.0005114705,0.000002770868,0.000004119795,0.00008357413,0.000003472214,0.00081202,0.9975376,0.0000210612,0.0009735239,0.000003227429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9602061,0.00121709,0.03578132,0.0001399029,0.00002638963,0.00005130244,0.0002872409,0.0002065744,0.002084116],"genre_scores_gemma":[0.9461281,0.001050939,0.05046884,0.00007896846,0.000009268416,0.00007336085,0.0004453108,0.00004924322,0.001695943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006579624,"threshold_uncertainty_score":0.002612829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09967247562143151,"score_gpt":0.3534265310033117,"score_spread":0.2537540553818802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}