{"id":"W3042134821","doi":"10.1007/s00784-020-03443-w","title":"Re-focusing on Agnathia-Otocephaly complex","year":2020,"lang":"en","type":"review","venue":"Clinical Oral Investigations","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Microstomia; Hypoplasia; Consanguinity; Medicine; ABCA4; Genetics; Phenotype; Biology; Gene; Pediatrics; Anatomy; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005529043,0.0005188349,0.001595236,0.00007513284,0.0002391972,0.00006107837,0.0005199349,0.0007111252,0.00004267308],"category_scores_gemma":[0.00421468,0.0004478394,0.0009561726,0.0003359622,0.0006947051,0.000003310705,0.0003462656,0.000763227,0.0005177221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003593707,"about_ca_system_score_gemma":0.0006833432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005336892,"about_ca_topic_score_gemma":0.00002493927,"domain_scores_codex":[0.9964291,0.0006409317,0.001402816,0.0009720249,0.0002196685,0.0003354914],"domain_scores_gemma":[0.9978237,0.0003935605,0.0005300303,0.0007137487,0.0001302113,0.0004087548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001672358,0.0002791742,0.0000899836,0.002586791,0.00100977,0.00005910379,0.00005002806,0.00001420037,0.0001441867,0.0009738624,0.1313818,0.8633943],"study_design_scores_gemma":[0.0001899105,0.0004116628,0.00001500647,0.001879852,0.0004394279,0.000003939612,0.00001293544,0.00001128475,0.00004153323,0.0001932616,0.996345,0.0004561229],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007823531,0.9944839,0.0001671388,0.001098101,0.0005632166,0.0009383343,0.0002446979,0.00008643771,0.002339919],"genre_scores_gemma":[0.0001497954,0.9892998,0.003706501,0.003059586,0.001916349,0.0001394473,0.001198229,0.000108769,0.0004214635],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8649632,"threshold_uncertainty_score":0.9997973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4615573965109489,"score_gpt":0.4888371705947614,"score_spread":0.02727977408381249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}