{"id":"W3042220572","doi":"10.4049/jimmunol.1900902","title":"Zebrafish <i>phd3</i> Negatively Regulates Antiviral Responses via Suppression of Irf7 Transactivity Independent of Its Prolyl Hydroxylase Activity","year":2020,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Agriculture","funders":"","keywords":"IRF7; Biology; Hydroxylation; Zebrafish; Transcription factor; Cell biology; Ubiquitin; Function (biology); Gene; Enzyme; Biochemistry; HEK 293 cells","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001084175,0.0002782303,0.0001606285,0.0001860978,0.0001915683,0.0001990639,0.0002337484,0.000319601,0.002467647],"category_scores_gemma":[0.00007889873,0.0001233493,0.0003020067,0.00006448328,0.0003245015,0.0001640334,0.000218478,0.0005324439,0.0005682931],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000501412,"about_ca_system_score_gemma":0.0002959464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002478305,"about_ca_topic_score_gemma":0.004193424,"domain_scores_codex":[0.9998866,0.00001036223,0.000008453515,0.00003224373,0.00003258923,0.00002974574],"domain_scores_gemma":[0.9999107,0.000007243044,0.00003556973,0.000008936488,0.00001016743,0.00002744533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002874222,0.000002277532,0.00007497345,0.0000107534,0.000001535744,0.00002352842,0.000002508147,0.00001336846,0.9994912,0.00005566985,0.0000394926,0.000255909],"study_design_scores_gemma":[0.0000197851,0.00007865837,0.007749437,0.000004940113,0.00001280403,0.0002377945,0.00002491253,0.0009581875,0.9871647,0.00006523477,0.003676344,0.000007248142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887998,0.0008520438,0.005107916,0.0003479521,0.00006662734,0.00002060349,0.001133307,0.0003091421,0.00336265],"genre_scores_gemma":[0.992246,0.0002142907,0.001484613,0.0001117041,0.000009113077,0.00001736411,0.0005392007,0.00005109621,0.005326573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002478305,"threshold_uncertainty_score":0.008255124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01213602948475145,"score_gpt":0.2403144001598946,"score_spread":0.2281783706751432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}