{"id":"W3042334584","doi":"10.1213/ane.0000000000004967","title":"Safety and Efficacy of the Combination of Propofol and Ketamine for Procedural Sedation/Anesthesia in the Pediatric Population: A Systematic Review and Meta-analysis","year":2020,"lang":"en","type":"review","venue":"Anesthesia & Analgesia","topic":"Anesthesia and Sedative Agents","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Impact; SickKids Foundation; Hospital for Sick Children; McMaster University; University of Toronto","funders":"","keywords":"Medicine; Propofol; Ketamine; Adverse effect; Anesthesia; Sedation; Meta-analysis; Regimen; Systematic review; Randomized controlled trial; Population; Intensive care medicine; MEDLINE; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01553452,0.002830835,0.02049715,0.0081226,0.0006965582,0.003593391,0.002466958,0.002652521,0.003380967],"category_scores_gemma":[0.03882343,0.001669811,0.04599548,0.00808464,0.0008383876,0.002115182,0.001588885,0.002050868,0.0002596858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003178352,"about_ca_system_score_gemma":0.004686175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006519042,"about_ca_topic_score_gemma":0.01240585,"domain_scores_codex":[0.9859865,0.005981513,0.004541308,0.001331024,0.001800799,0.0003589159],"domain_scores_gemma":[0.9733723,0.01899659,0.004937274,0.0006149721,0.001807997,0.0002709348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001324082,0.00003257629,0.003111474,0.4516676,0.532587,0.0001038281,0.0000740497,0.000414212,0.0001404447,0.00009331114,0.000353048,0.01009842],"study_design_scores_gemma":[0.0004416512,0.0001996206,0.002849213,0.03091879,0.9640421,0.0001044242,0.00003741236,0.0001602984,0.00009483765,0.000120809,0.001009135,0.0000217891],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004027952,0.9943708,0.0004327182,0.0001676106,0.0001116829,0.0003316567,0.0003563109,0.00001704713,0.0001842471],"genre_scores_gemma":[0.1323609,0.8611134,0.002843165,0.0008172258,0.0002768778,0.001626117,0.0006877969,0.00002641983,0.000248154],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02049715,"threshold_uncertainty_score":0.08215541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05191743376643115,"score_gpt":0.3271039370363574,"score_spread":0.2751865032699263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}