{"id":"W3042487759","doi":"10.2147/por.s251120","title":"<p>The CHRONICLE Study of US Adults with Subspecialist-Treated Severe Asthma: Objectives, Design, and Initial Results</p>","year":2020,"lang":"en","type":"article","venue":"Pragmatic and Observational Research","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Institutes of Health; Baxalta; AstraZeneca; CSL Behring; Genentech; Grifols; Valeant Pharmaceuticals International; Sanofi; Mylan; GlaxoSmithKline; Regeneron Pharmaceuticals; Teva Pharmaceutical Industries; Horizon Pharma; Pfizer","keywords":"Pulmonologist; Medicine; Asthma; Exacerbation; Cohort; Pediatrics; Internal medicine; Family medicine; Intensive care medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007698342,0.0006633467,0.000461436,0.0005205505,0.001174655,0.001120387,0.001113481,0.00104541,0.008705938],"category_scores_gemma":[0.005027166,0.000562773,0.0005658463,0.001219856,0.001007135,0.001302391,0.001337866,0.00106133,0.002763725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001389871,"about_ca_system_score_gemma":0.004300492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004728486,"about_ca_topic_score_gemma":0.01184383,"domain_scores_codex":[0.9963246,0.002174296,0.000298442,0.000545006,0.0003979054,0.0002597671],"domain_scores_gemma":[0.9949208,0.0006616766,0.001878076,0.0004574051,0.0008754554,0.001206565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02356446,0.005557707,0.836625,0.002572132,0.0008501552,0.0003651599,0.0008710983,0.0003129386,0.00162644,0.002097273,0.07837238,0.04718531],"study_design_scores_gemma":[0.03752227,0.0183849,0.8691727,0.002040669,0.0008400542,0.0006753225,0.001349483,0.001176933,0.0009854812,0.00146116,0.06630889,0.00008217804],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.7477205,0.006048579,0.005821003,0.009663697,0.0005396741,0.1261914,0.07580372,0.0002066981,0.02800473],"genre_scores_gemma":[0.7752206,0.001762974,0.01156032,0.009391545,0.0009229095,0.1725157,0.02234932,0.00007900122,0.006197495],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.008705938,"threshold_uncertainty_score":0.04071319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08460424390656908,"score_gpt":0.3457514705845573,"score_spread":0.2611472266779882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}