{"id":"W3042561281","doi":"10.1101/2020.07.13.201319","title":"Regional Differences in the Ghrelin-Growth Hormone Secretagogue Receptor Signalling System in Human Heart Disease","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; Lawson Health Research Institute; University of Toronto; University Health Network; Western University","funders":"","keywords":"Ghrelin; Growth hormone secretagogue receptor; Internal medicine; Endocrinology; Contractility; Heart failure; Ejection fraction; Cardiomyopathy; Receptor; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002067443,0.0001258822,0.000211654,0.0005322663,0.0001043451,0.0001940181,0.0000717299,0.0002089875,0.001104839],"category_scores_gemma":[0.0002809351,0.0001114836,0.0001095592,0.0002245576,0.0002127327,0.0001226697,0.0001371339,0.0001566044,0.0001698986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000942749,"about_ca_system_score_gemma":0.00004972103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004158532,"about_ca_topic_score_gemma":0.0004137257,"domain_scores_codex":[0.999928,0.00001991641,0.000004957104,0.00002418021,0.00001129659,0.00001160647],"domain_scores_gemma":[0.9998872,0.0000348996,0.0000313548,0.000007967033,0.00001277732,0.00002576365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002358183,0.00005911227,0.2693886,0.0001098127,0.000130189,0.001625305,0.0004411757,0.0003138482,0.7142662,0.0003227579,0.0001950505,0.01078967],"study_design_scores_gemma":[0.000009133654,0.00009833905,0.9942845,0.000003357002,0.00001968111,0.0008702915,0.00008334314,0.000235801,0.004151289,0.00006314283,0.0001773736,0.000003813324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978046,0.001261689,0.0003706179,0.00002235999,0.000004158775,0.000004436012,0.00006824197,0.000006153333,0.000457651],"genre_scores_gemma":[0.9993278,0.0002212039,0.0001948808,0.00001638858,0.000006800458,0.000006070579,0.00007071563,0.000001881372,0.0001543881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001104839,"threshold_uncertainty_score":0.003696024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0395547758524666,"score_gpt":0.2360482126186134,"score_spread":0.1964934367661468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}