{"id":"W3042635246","doi":"10.1016/j.bbi.2020.07.018","title":"Decreased motor impulsivity following chronic lithium treatment in male rats is associated with reduced levels of pro-inflammatory cytokines in the orbitofrontal cortex","year":2020,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; University of British Columbia; Michael Smith Health Research BC","keywords":"Impulsivity; Lithium (medication); Nucleus accumbens; Prefrontal cortex; Psychology; Orbitofrontal cortex; Internal medicine; Bipolar disorder; Medicine; Cytokine; Endocrinology; Psychiatry; Central nervous system; Cognition","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007483602,0.0005101028,0.000584292,0.0007103369,0.0003643573,0.0003665268,0.0001918336,0.0003812012,0.002629877],"category_scores_gemma":[0.0001360204,0.0003557687,0.0002948329,0.0002569567,0.0005694467,0.0002624787,0.0002254589,0.0008484675,0.0002169483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006968639,"about_ca_system_score_gemma":0.0004843202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00436652,"about_ca_topic_score_gemma":0.01499128,"domain_scores_codex":[0.9999043,0.00001247706,0.000006931574,0.0000180623,0.0000252545,0.00003300247],"domain_scores_gemma":[0.9997303,0.000009431405,0.0001184771,0.00001696208,0.0000186698,0.0001061098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01132789,0.0007099354,0.006205305,0.000108962,0.0000815423,0.0001710783,0.0000895514,0.00004750998,0.9756881,0.0001142528,0.0002568333,0.005199033],"study_design_scores_gemma":[0.001035818,0.01137203,0.3647866,0.00007538682,0.0003790234,0.0008712386,0.0009671403,0.001897801,0.6156293,0.0004545276,0.002438663,0.00009247808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982376,0.0004521305,0.0002812206,0.0001552963,0.00003033259,0.00001187113,0.0003150812,0.00004874889,0.0004677063],"genre_scores_gemma":[0.9953026,0.0006443894,0.0005988502,0.0001204433,0.00001949357,0.00006550556,0.0004097988,0.00002403638,0.002815011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00436652,"threshold_uncertainty_score":0.008797824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02850540031754966,"score_gpt":0.2803658396324821,"score_spread":0.2518604393149325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}