{"id":"W3042924866","doi":"10.1182/blood.2020004976","title":"Sustained depletion of FXIII-A by inducing acquired FXIII-B deficiency","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Blood properties and coagulation","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; Canadian Institutes of Health Research; Michael Smith Health Research BC; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"Fibrinolysis; Factor XIII; Fibrin; In vivo; Ex vivo; Medicine; Pharmacology; Coagulation; Platelet; Antifibrinolytic; Chemistry; Immunology; In vitro; Internal medicine; Biochemistry; Biology; Surgery; Tranexamic acid; Blood loss","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000254368,0.0003186256,0.0003305801,0.0001779527,0.00008930743,0.0002830129,0.0002032031,0.0002998495,0.0009785052],"category_scores_gemma":[0.0001558374,0.0001228822,0.0002391627,0.0001035488,0.0002909093,0.000184975,0.0001984904,0.000636803,0.000232345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002091992,"about_ca_system_score_gemma":0.0002022141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000374751,"about_ca_topic_score_gemma":0.000332204,"domain_scores_codex":[0.9998385,0.00003048043,0.00002529128,0.0000430851,0.00003437927,0.00002836459],"domain_scores_gemma":[0.9998819,0.00001859455,0.00004273992,0.00001726648,0.00001097895,0.00002854093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001675586,0.00006450381,0.00005201303,0.00003388073,0.000007544982,0.00003805943,0.00001270301,0.00005206718,0.9980378,0.0001517235,0.00006159424,0.00132068],"study_design_scores_gemma":[0.00006757796,0.001267862,0.0006822295,0.000005233354,0.00002091757,0.0002280802,0.000008017672,0.000802414,0.9942067,0.00004704022,0.002660572,0.000003354832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840658,0.00198818,0.01145866,0.0001879388,0.00007531118,0.0001306118,0.0003619007,0.0002767466,0.001454805],"genre_scores_gemma":[0.9902545,0.001004169,0.005460329,0.00008264941,0.00002429471,0.0001316752,0.0003085229,0.00003818891,0.002695578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009785052,"threshold_uncertainty_score":0.003273427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01992739597251521,"score_gpt":0.2291123445124759,"score_spread":0.2091849485399607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}