{"id":"W3042924866","doi":"10.1182/blood.2020004976","title":"Sustained depletion of FXIII-A by inducing acquired FXIII-B deficiency","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Blood properties and coagulation","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; Canadian Institutes of Health Research; Michael Smith Health Research BC; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"Fibrinolysis; Factor XIII; Fibrin; In vivo; Ex vivo; Medicine; Pharmacology; Coagulation; Platelet; Antifibrinolytic; Chemistry; Immunology; In vitro; Internal medicine; Biochemistry; Biology; Surgery; Tranexamic acid; Blood loss","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008762818,0.00009909855,0.0002138498,0.00003401762,0.00004724218,0.000009486714,0.00006574356,0.00008164643,0.0001052105],"category_scores_gemma":[0.0001220281,0.00008433985,0.000062236,0.0002437178,0.00003222754,0.00006977087,0.00005094012,0.00006761617,0.00001656275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001092103,"about_ca_system_score_gemma":0.0000649225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006096511,"about_ca_topic_score_gemma":0.000001198305,"domain_scores_codex":[0.9991184,0.00002542898,0.0002575499,0.0001998109,0.0002241832,0.0001745981],"domain_scores_gemma":[0.9995287,0.00001488411,0.00009031926,0.0001599615,0.0001028149,0.0001032975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003910527,0.001007514,0.05733234,0.0005949287,0.0001203729,0.00002118137,0.00265409,0.00001853475,0.9239899,0.0003913277,0.002977261,0.01050149],"study_design_scores_gemma":[0.01844444,0.004306444,0.0575255,0.0003360681,0.001311381,0.00008259951,0.004021464,0.001885783,0.9066128,0.0003306927,0.004470611,0.0006722345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993468,0.001211154,0.0004436154,0.002225203,0.0000333724,0.0002575548,0.000006859514,0.00007185402,0.002282406],"genre_scores_gemma":[0.9986892,0.00002391771,0.0002994404,0.0006945803,0.0001126882,0.000007641225,0.00004432067,0.00001802958,0.0001102001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01805338,"threshold_uncertainty_score":0.3439279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01992739597251521,"score_gpt":0.2291123445124759,"score_spread":0.2091849485399607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}