{"id":"W3042928905","doi":"10.3390/v12070755","title":"Innate Immune Sensing of Influenza A Virus","year":2020,"lang":"en","type":"review","venue":"Viruses","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Public Health Agency of Canada","keywords":"Innate immune system; Pattern recognition receptor; RIG-I; Interferon; Biology; Influenza A virus; Virus; Virology; Immune system; Proinflammatory cytokine; Pyrin domain; Immunology; MDA5; Viral replication; Inflammasome; Inflammation; Gene; RNA interference; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002510304,0.0007004167,0.0007565651,0.001198071,0.0002073107,0.0006183567,0.0005505912,0.0006392103,0.003121078],"category_scores_gemma":[0.0002284866,0.0001978323,0.0002899656,0.001037165,0.0002604155,0.0008524894,0.0005661268,0.001292172,0.00280938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000420293,"about_ca_system_score_gemma":0.0006263404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005393868,"about_ca_topic_score_gemma":0.0007148464,"domain_scores_codex":[0.9998919,0.00001774974,0.00001321625,0.0000186033,0.00004346628,0.00001504953],"domain_scores_gemma":[0.999926,0.0000215575,0.0000124037,0.00000293616,0.00002352871,0.00001365467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007459814,0.00005951931,0.0001475084,0.01389331,0.00005908964,0.0002377716,0.00006179156,0.0003217063,0.00800382,0.004025679,0.04129884,0.9318165],"study_design_scores_gemma":[0.000006620466,0.00007285163,0.0005698787,0.001351234,0.00002761328,0.0008781904,0.00002826436,0.0000526233,0.0006352275,0.001272907,0.9950956,0.000009041186],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001655703,0.9971005,0.0001458387,0.0001629375,0.0003609485,0.000005013111,0.00001736669,0.000009490939,0.002032208],"genre_scores_gemma":[0.0008604313,0.9974015,0.000136712,0.0001450957,0.0002171625,0.000005293812,0.0000426509,0.00000147872,0.001189681],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003121078,"threshold_uncertainty_score":0.01044106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07778057556814046,"score_gpt":0.3505998385159559,"score_spread":0.2728192629478154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}