{"id":"W3043099150","doi":"10.1182/bloodadvances.2019001266","title":"Reduced intensity conditioning for acute myeloid leukemia using melphalan- vs busulfan-based regimens: a CIBMTR report","year":2020,"lang":"en","type":"article","venue":"Blood Advances","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"Moonshot Research and Development Program; National Institute of Allergy and Infectious Diseases; Office of Naval Research; Takeda Oncology; Genentech; Health Resources and Services Administration; National Institutes of Health; MacroGenics; Omeros Corporation; Janssen Scientific Affairs; Mundipharma EDO; Astellas Pharma; Adaptive Biotechnologies; Pfizer; Incyte; CTI Biopharma; bluebird bio; Cancer Moonshot; Chimerix; Medac; Jazz Pharmaceuticals; Janssen Biotech; HistoGenetics; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Celgene; Karyopharm Therapeutics; Atara Biotherapeutics; Actinium Pharmaceuticals; Daiichi Sankyo Europe; National Cancer Institute; Gilead Sciences; Biomedical Advanced Research and Development Authority; Amgen; CSL Behring; Bristol-Myers Squibb; Janssen Pharmaceuticals; Memorial Sloan-Kettering Cancer Center; GlaxoSmithKline; Agios Pharmaceuticals; Sierra Oncology; Astellas Pharma US","keywords":"Medicine; Busulfan; Fludarabine; Melphalan; Internal medicine; Total body irradiation; Alemtuzumab; Hazard ratio; Transplantation; Myeloid leukemia; Gastroenterology; Surgery; Leukemia; Oncology; Hematopoietic stem cell transplantation; Chemotherapy; Cyclophosphamide; Confidence interval","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002064797,0.0002249477,0.0005462637,0.00007122318,0.0001518209,0.00002559721,0.0000851903,0.0001006562,0.00003562877],"category_scores_gemma":[0.000315331,0.0002156278,0.0001462138,0.0002404034,0.00008507892,0.0001859069,0.00001202552,0.0001618145,0.000009278781],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008818002,"about_ca_system_score_gemma":0.0004089113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001497188,"about_ca_topic_score_gemma":0.000002718954,"domain_scores_codex":[0.9982805,0.00002721229,0.0005204846,0.0005201429,0.0003124364,0.0003391914],"domain_scores_gemma":[0.9987673,0.0001644664,0.00029433,0.0002670826,0.0002801302,0.0002266679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002434096,0.0001770607,0.007886508,0.001726012,0.0007276738,0.002958063,0.001258122,0.000866674,0.9804021,0.0001879094,0.0005716886,0.0008040905],"study_design_scores_gemma":[0.005963027,0.0006689618,0.002699073,0.000925537,0.002350659,0.002476642,0.000481837,0.005593616,0.9747238,0.0001614324,0.003549893,0.0004055509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9642501,0.0005268513,0.02977603,0.002836565,0.000309924,0.001162962,0.00006843081,0.000275719,0.0007934133],"genre_scores_gemma":[0.9483889,0.00006104119,0.04881271,0.001784764,0.0003358151,0.00006804544,0.0003874329,0.00004830872,0.000112939],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01903667,"threshold_uncertainty_score":0.8793048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0338867392681122,"score_gpt":0.3146726970560506,"score_spread":0.2807859577879384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}