{"id":"W3043205384","doi":"10.1083/jcb.201910041","title":"PTEN dephosphorylates Abi1 to promote epithelial morphogenesis","year":2020,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Cancer Institute","keywords":"PTEN; Cell biology; Tensin; Phosphatase; Biology; Actin cytoskeleton; Chemistry; PI3K/AKT/mTOR pathway; Cytoskeleton; Signal transduction; Phosphorylation; Biochemistry; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009922054,0.0002423567,0.0001090488,0.0002174646,0.0001701125,0.000261737,0.0001652899,0.0001437596,0.001309974],"category_scores_gemma":[0.00008147076,0.000139524,0.0001633525,0.0001348185,0.000163571,0.0001691117,0.0002205647,0.0004219757,0.000451165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002872871,"about_ca_system_score_gemma":0.0003420128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008786995,"about_ca_topic_score_gemma":0.001766162,"domain_scores_codex":[0.9999176,0.000008548911,0.00000665678,0.00001215071,0.00003145933,0.00002349492],"domain_scores_gemma":[0.999953,0.000006552796,0.00001461436,0.000004612931,0.000004732205,0.00001639517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004613998,0.00001379321,0.000153418,0.00002341418,0.000002590274,0.00005591997,0.00000791361,0.00008053044,0.9983866,0.0002018339,0.00004324871,0.0009845698],"study_design_scores_gemma":[0.000008215747,0.00005184284,0.003736014,0.000002217783,0.000005362852,0.0001930607,0.0000115835,0.0009857632,0.9925904,0.0000718175,0.002341742,0.000002115396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910064,0.001544619,0.003832438,0.0001654632,0.00002792203,0.00002225726,0.0003411793,0.0001403213,0.002919255],"genre_scores_gemma":[0.9952324,0.0007660915,0.001262145,0.00004306499,0.000005799535,0.0000130424,0.0002667793,0.00001478688,0.002395817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001309974,"threshold_uncertainty_score":0.004382253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0120853322455146,"score_gpt":0.2423381258507864,"score_spread":0.2302527936052718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}