{"id":"W3043220890","doi":"10.3389/fgene.2020.00636","title":"Poly(A) Binding Protein Is Required for Nuclear Localization of the Ecdysteroidogenic Transcription Factor Molting Defective in the Prothoracic Gland of Drosophila melanogaster","year":2020,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Core Research for Evolutional Science and Technology; Institute of Genetics; Japan Agency for Medical Research and Development","keywords":"Prothoracic gland; Biology; Transcription factor; Ecdysone; Drosophila melanogaster; RNA interference; Cell biology; Zinc finger transcription factor; Transcriptional regulation; Regulation of gene expression; Repressor; Ecdysone receptor; Zinc finger; Transcription (linguistics); Molecular biology; Nuclear receptor; Gene; Genetics; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007819957,0.0005696249,0.0001778835,0.0002222512,0.0002591827,0.0003030237,0.0002538101,0.0002897647,0.002247615],"category_scores_gemma":[0.0001034149,0.0002455082,0.000313673,0.0001234288,0.000294283,0.0001725206,0.0003122429,0.0006420485,0.001054508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004428189,"about_ca_system_score_gemma":0.0002267879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00148272,"about_ca_topic_score_gemma":0.002570534,"domain_scores_codex":[0.99986,0.00001322357,0.00001529179,0.00004760555,0.00004056922,0.00002334409],"domain_scores_gemma":[0.9998032,0.00002040858,0.00006481863,0.00001903762,0.00001239105,0.00008010821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003406431,0.000008404108,0.0001601612,0.00002457309,0.000003435458,0.00008078165,0.000008236411,0.00001816271,0.9992428,0.00006907611,0.00003368164,0.000316745],"study_design_scores_gemma":[0.00006095578,0.0001459758,0.04132125,0.00002566049,0.00004690011,0.0007666,0.00007307025,0.002296922,0.946666,0.0001312542,0.008450696,0.00001477724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889732,0.00222191,0.004281696,0.0001738428,0.0001164481,0.00003583425,0.001436525,0.0002922135,0.00246822],"genre_scores_gemma":[0.9901968,0.0005897104,0.001466189,0.00009096126,0.00001554105,0.00003660871,0.00192896,0.00007147207,0.005603604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002247615,"threshold_uncertainty_score":0.007518947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04930621908529195,"score_gpt":0.2776594964460173,"score_spread":0.2283532773607254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}