{"id":"W3043220890","doi":"10.3389/fgene.2020.00636","title":"Poly(A) Binding Protein Is Required for Nuclear Localization of the Ecdysteroidogenic Transcription Factor Molting Defective in the Prothoracic Gland of Drosophila melanogaster","year":2020,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Core Research for Evolutional Science and Technology; Institute of Genetics; Japan Agency for Medical Research and Development","keywords":"Prothoracic gland; Biology; Transcription factor; Ecdysone; Drosophila melanogaster; RNA interference; Cell biology; Zinc finger transcription factor; Transcriptional regulation; Regulation of gene expression; Repressor; Ecdysone receptor; Zinc finger; Transcription (linguistics); Molecular biology; Nuclear receptor; Gene; Genetics; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001602963,0.00009592904,0.0001773879,0.00007568869,0.00008203962,0.000008700365,0.0003633079,0.0001021672,0.000003952671],"category_scores_gemma":[0.0001878193,0.00006555569,0.00006991556,0.0003808622,0.0002293833,0.0000563535,0.0000443183,0.0001866876,7.322049e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001973791,"about_ca_system_score_gemma":0.00002715066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002459817,"about_ca_topic_score_gemma":0.000002262336,"domain_scores_codex":[0.9986469,0.0005082263,0.0002692209,0.0002531845,0.000129156,0.000193331],"domain_scores_gemma":[0.9995934,0.00005776363,0.0001362793,0.0001678911,0.00002647129,0.00001819634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003037486,0.00003892006,0.01362626,0.00009959796,0.000004942662,6.24416e-7,0.004606656,0.00007624925,0.9807179,0.00002519791,0.0000337378,0.0004661948],"study_design_scores_gemma":[0.000594716,0.0004533705,0.003338118,0.00004911001,0.000008141715,0.000001885451,0.0003447834,0.01049011,0.9840477,0.0005377861,0.00006302581,0.00007124263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957578,0.00009535654,0.002023649,0.0003722525,0.0001153946,0.001562303,0.00004701414,0.000005714427,0.00002050979],"genre_scores_gemma":[0.9992852,0.00001790503,0.000303504,0.0002999479,0.0000205489,0.00004682399,0.000002132608,0.00001508095,0.000008820213],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01041386,"threshold_uncertainty_score":0.2673284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04930621908529195,"score_gpt":0.2776594964460173,"score_spread":0.2283532773607254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}