{"id":"W3043266198","doi":"10.1002/jbmr.4133","title":"Bisphosphonate Use Is Protective of Radiographic Knee Osteoarthritis Progression Among those With Low Disease Severity and Being Non-Overweight: Data From the Osteoarthritis Initiative","year":2020,"lang":"en","type":"article","venue":"Journal of Bone and Mineral Research","topic":"Bone health and treatments","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Women's College Hospital; Public Health Ontario; University of Toronto","funders":"Institute of Population and Public Health; National Institute of Mental Health; Canadian Institutes of Health Research; U.S. Department of Health and Human Services; National Institutes of Health; Novartis Pharmaceuticals Corporation; Pfizer; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Foundation for the National Institutes of Health","keywords":"Medicine; Bisphosphonate; Osteoarthritis; Overweight; Internal medicine; Body mass index; Cohort; Hazard ratio; Physical therapy; Surgery; Osteoporosis; Confidence interval; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001273302,0.0003132194,0.0004126107,0.000648831,0.0003768352,0.000684869,0.0004855699,0.0004315735,0.002486905],"category_scores_gemma":[0.003192556,0.000315535,0.001394122,0.0009954988,0.0001354162,0.0002886139,0.0004983064,0.0007576444,0.0003119126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001274917,"about_ca_system_score_gemma":0.0003069701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009089121,"about_ca_topic_score_gemma":0.009865243,"domain_scores_codex":[0.999236,0.0002260635,0.0001213943,0.0001651628,0.000141283,0.0001101112],"domain_scores_gemma":[0.9972749,0.0004270881,0.001358264,0.0002889323,0.0002784232,0.0003723821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008331334,0.00006320633,0.9971065,0.000040991,0.0003900171,0.00002485025,0.00004299328,0.00002254194,0.0001346578,0.00001921118,0.0002333721,0.001088603],"study_design_scores_gemma":[0.00005419054,0.0001845506,0.9986959,0.0000202666,0.0003036368,0.0000762862,0.00009844696,0.0001484509,0.00004039242,0.00001995746,0.0003537072,0.000004226427],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994261,0.001010823,0.0001985462,0.000112306,0.00002274774,0.00002131694,0.003698006,0.00000635386,0.0006689624],"genre_scores_gemma":[0.9974046,0.0002770132,0.0001104194,0.00004777053,0.00002260764,0.00001978919,0.001789876,0.000003823168,0.000324109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009089121,"threshold_uncertainty_score":0.01807243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06506778902268613,"score_gpt":0.3476185687340869,"score_spread":0.2825507797114007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}