{"id":"W3043306280","doi":"10.1136/annrheumdis-2020-eular.346","title":"OP0231 COMPARATIVE EFFECTIVENESS OF JAK-INHIBITORS, TNF-INHIBITORS, ABATACEPT AND IL-6 INHIBITORS IN AN INTERNATIONAL COLLABORATION OF REGISTERS OF RHEUMATOID ARTHRITIS PATIENTS (THE “JAK-POT” STUDY)","year":2020,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"Pfizer; Eli Lilly and Company","keywords":"Abatacept; Medicine; Rheumatoid arthritis; TNF inhibitor; Tofacitinib; Methotrexate; Arthritis; Internal medicine; Immunology; Pharmacology; Oncology; Adalimumab; Rituximab; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002913905,0.001188615,0.001988684,0.0007959077,0.0004213037,0.001432695,0.000733084,0.001344426,0.002649768],"category_scores_gemma":[0.003686644,0.0006647567,0.003223285,0.001554712,0.0005523918,0.001163737,0.0009601297,0.001262818,0.0003064484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005708943,"about_ca_system_score_gemma":0.001132326,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004058807,"about_ca_topic_score_gemma":0.007000553,"domain_scores_codex":[0.9977074,0.001308852,0.0001796109,0.0003688088,0.0001802407,0.0002551391],"domain_scores_gemma":[0.9975107,0.0009525226,0.0007658276,0.0002704196,0.0001261828,0.0003743932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8239614,0.001882378,0.1327567,0.0009751729,0.01371523,0.0002960265,0.0002772205,0.0007958435,0.002661568,0.0002818059,0.001670233,0.02072651],"study_design_scores_gemma":[0.2534633,0.05507269,0.6629877,0.0002921026,0.02224083,0.0005497686,0.0006813309,0.0009406832,0.0007052901,0.0003592714,0.002566526,0.0001404647],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938323,0.003479993,0.00005463052,0.0001058583,0.00005557938,0.00006883431,0.001634425,0.000007353986,0.0007609943],"genre_scores_gemma":[0.9940537,0.00160797,0.0001760374,0.0001611999,0.0001197351,0.0001004327,0.003346735,0.000006221764,0.0004279846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004058807,"threshold_uncertainty_score":0.01541042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04151861357584468,"score_gpt":0.325950423299203,"score_spread":0.2844318097233584,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}