{"id":"W3043308024","doi":"10.7326/m20-4207","title":"Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19","year":2020,"lang":"en","type":"article","venue":"Annals of Internal Medicine","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":548,"is_retracted":false,"has_abstract":true,"ca_institutions":"George & Fay Yee Centre for Healthcare Innovation; University of Manitoba; University of Alberta; McGill University Health Centre","funders":"National Center for Advancing Translational Sciences; Fogarty International Center; National Institute of Allergy and Infectious Diseases; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Doris Duke Charitable Foundation","keywords":"Hydroxychloroquine; Medicine; Placebo; Clinical endpoint; Internal medicine; Adverse effect; Severity of illness; Randomized controlled trial; Coronavirus disease 2019 (COVID-19); Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001089483,0.0002258042,0.0006646496,0.0001340961,0.0001850838,0.0003245838,0.0002645131,0.0005650901,0.002533204],"category_scores_gemma":[0.0017708,0.0001067464,0.0004608229,0.0001942183,0.0002186653,0.0001772802,0.0001549555,0.0006152203,0.0001536878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003699086,"about_ca_system_score_gemma":0.0008930937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001060482,"about_ca_topic_score_gemma":0.003238277,"domain_scores_codex":[0.999593,0.000243011,0.00003938194,0.00003664693,0.00004424428,0.00004384637],"domain_scores_gemma":[0.9987869,0.0004026878,0.0004457335,0.00003236635,0.0001058973,0.0002265168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5238594,0.01944542,0.08441976,0.01443453,0.002585385,0.0004187786,0.0003400692,0.0004179593,0.01060999,0.0003877443,0.007078528,0.3360025],"study_design_scores_gemma":[0.4963724,0.3066469,0.1787441,0.002529152,0.002121678,0.0005297426,0.000301169,0.0005580648,0.002432648,0.0003038146,0.009436836,0.00002362978],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9428022,0.0509707,0.0002196728,0.001421845,0.0002809313,0.001109582,0.0004054719,0.00001471044,0.00277479],"genre_scores_gemma":[0.9876629,0.009572243,0.000419973,0.000805671,0.0003029187,0.0005283309,0.0002493795,0.000001820605,0.0004567873],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002533204,"threshold_uncertainty_score":0.00847441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0983396606637956,"score_gpt":0.4578260633492532,"score_spread":0.3594864026854576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}