{"id":"W3043322250","doi":"10.3390/cancers12071926","title":"Metabolites as Prognostic Markers for Metastatic Non-Small Cell Lung Cancer (NSCLC) Patients Treated with First-Line Platinum-Doublet Chemotherapy","year":2020,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; Queen's University; University of Calgary","funders":"Alberta Innovates; Canadian Cancer Society; National Institutes of Health; Alberta Cancer Foundation","keywords":"Internal medicine; Hazard ratio; Medicine; Oncology; Lung cancer; Proportional hazards model; Confidence interval; Chemotherapy; Gastroenterology; Clinical endpoint; Clinical trial","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007125098,0.0003765466,0.0004287708,0.00004121638,0.0001156256,0.00004232631,0.0002374861,0.00009941886,0.00007762387],"category_scores_gemma":[0.00006641159,0.0003193025,0.0001633486,0.0002197227,0.00008757081,0.00001128647,0.00003733971,0.00009974387,0.000003071581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001292138,"about_ca_system_score_gemma":0.0009042839,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004916506,"about_ca_topic_score_gemma":0.0004079083,"domain_scores_codex":[0.9983695,0.00002995309,0.0002940623,0.0006466328,0.0001730722,0.000486792],"domain_scores_gemma":[0.9989921,0.00003919607,0.0002019758,0.0002680479,0.0002287426,0.0002699302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.02590748,0.0005468616,0.2651127,0.004287241,0.00524277,0.000003578903,0.004162778,0.02332357,0.2465851,0.00006497278,0.3937314,0.03103157],"study_design_scores_gemma":[0.01929182,0.002070876,0.006659104,0.000184328,0.001124283,0.000002284109,0.0002860626,0.00281263,0.1654253,0.00000653577,0.8009693,0.001167429],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860268,0.006481156,0.002134092,0.0004167223,0.001304867,0.002390336,0.0004655863,0.00004276075,0.0007376481],"genre_scores_gemma":[0.9783792,0.004640857,0.002432448,0.004665076,0.005421723,0.00188604,0.0009191654,0.0001996581,0.001455764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4072379,"threshold_uncertainty_score":0.9999259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009909753016621994,"score_gpt":0.2407205708903888,"score_spread":0.2308108178737668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}