{"id":"W3043391491","doi":"10.1186/s13073-020-00763-0","title":"Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein","year":2020,"lang":"en","type":"article","venue":"Genome Medicine","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":513,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; U.S. Food and Drug Administration; Biotechnology and Biological Sciences Research Council; Public Health England; University of Melbourne; Hamilton Health Sciences Foundation; National Institute for Health and Care Research; National Institute for Health Research Health Protection Research Unit","keywords":"Furin; Proteome; Cleavage (geology); Transcriptome; Glycoprotein; Computational biology; Biology; Cell; Open reading frame; Cell biology; Bioinformatics; Genetics; Gene; Peptide sequence; Biochemistry; Gene expression; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05282139358500089,"score_gpt":0.2961307797417582,"score_spread":0.2433093861567573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}