{"id":"W3043470896","doi":"10.1016/j.watres.2020.116107","title":"Reproduction stage specific dysregulation of Daphnia magna metabolites as an early indicator of reproductive endocrine disruption","year":2020,"lang":"en","type":"article","venue":"Water Research","topic":"Pharmaceutical and Antibiotic Environmental Impacts","field":"Environmental Science","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"University of Toronto","keywords":"Daphnia magna; Metabolite; Biology; Metabolomics; Reproduction; Metabolic pathway; Internal medicine; Toxicity; Endocrinology; Metabolism; Ecology; Bioinformatics; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005818092,0.0001987781,0.0001337237,0.0004172889,0.0001572612,0.0002856023,0.0001040445,0.0002597413,0.00117742],"category_scores_gemma":[0.0001026281,0.0001339356,0.000138406,0.000203406,0.0001788099,0.0001732746,0.00020781,0.0003931993,0.0001942128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002992889,"about_ca_system_score_gemma":0.0001680905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001871223,"about_ca_topic_score_gemma":0.004942237,"domain_scores_codex":[0.9999413,0.000004709092,0.000003104989,0.00002073769,0.00001239006,0.00001772043],"domain_scores_gemma":[0.9998769,0.00001560987,0.00005052719,0.000007815881,0.00001887698,0.0000303853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003663597,0.00003327267,0.01445356,0.00002872433,0.00001198346,0.00007980969,0.00005402481,0.00003055183,0.9824731,0.00003213438,0.0001029087,0.002333636],"study_design_scores_gemma":[0.000006375541,0.0005194159,0.7403482,0.000005290491,0.00003302621,0.0002207894,0.0002064164,0.0001747581,0.2569366,0.00004964842,0.00149023,0.000009268027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955494,0.0006605035,0.0006492874,0.00005560944,0.00001385784,0.00001711532,0.001509885,0.00004354395,0.001500865],"genre_scores_gemma":[0.9950495,0.0003238338,0.0006862593,0.00007034751,0.000004635269,0.00002857685,0.0009395994,0.000008604272,0.002888531],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001871223,"threshold_uncertainty_score":0.003938913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1005714643758861,"score_gpt":0.3719153887451678,"score_spread":0.2713439243692817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}