{"id":"W3043530209","doi":"10.1073/pnas.2005019117","title":"Clusters of bacterial RNA polymerase are biomolecular condensates that assemble through liquid–liquid phase separation","year":2020,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":270,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Intracellular; Eukaryotic cell; Bacteria; RNA; Cell biology; Biology; Liquid phase; Chemistry; Biophysics; Cell; Biochemistry; Genetics; Gene; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009573244,0.0002306573,0.0001634672,0.0003588765,0.000195439,0.000386407,0.0001535948,0.0001738083,0.0009507214],"category_scores_gemma":[0.0002881185,0.0002919757,0.0001454738,0.0001928688,0.0002844054,0.0003171161,0.0002190075,0.0002908034,0.0006574102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005018031,"about_ca_system_score_gemma":0.0002150447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001208395,"about_ca_topic_score_gemma":0.002128261,"domain_scores_codex":[0.9998811,0.00001153562,0.000005054729,0.00004200102,0.00004461797,0.00001566347],"domain_scores_gemma":[0.9998487,0.00003870086,0.00004703936,0.00001586868,0.00001896589,0.00003068034],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002595344,0.000004456412,0.0004639297,0.0000182979,0.000004385126,0.00003002082,0.00001771759,0.0002016886,0.9969382,0.0001929659,0.00003450778,0.002067852],"study_design_scores_gemma":[0.000009153412,0.00007480333,0.004370983,0.000004858388,0.000008029746,0.0001665203,0.00002432509,0.00440026,0.9883011,0.0002319204,0.002401898,0.00000612977],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9555452,0.001235939,0.03904485,0.00011446,0.00001697505,0.00006203959,0.0002682661,0.0003638655,0.00334843],"genre_scores_gemma":[0.9758635,0.0004080069,0.01919887,0.00003792545,0.00001284927,0.00004589299,0.0003772562,0.00007338044,0.003982382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001208395,"threshold_uncertainty_score":0.003640831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05952836207308315,"score_gpt":0.3622166806494691,"score_spread":0.302688318576386,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}