{"id":"W3043701315","doi":"10.1093/neuonc/noaa168","title":"CODEL: phase III study of RT, RT + TMZ, or TMZ for newly diagnosed 1p/19q codeleted oligodendroglioma. Analysis from the initial study design","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Cancer Institute; ECOG-ACRIN Cancer Research Group; National Institutes of Health; American College of Radiology Imaging Network; Alliance for Clinical Trials in Oncology Foundation","keywords":"Oligodendroglioma; Medicine; Oncology; Phases of clinical research; Internal medicine; Nuclear medicine; Glioma; Cancer research; Chemotherapy; Astrocytoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004033182,0.0004780033,0.001890144,0.0002993819,0.0002286899,0.00003753267,0.0004512832,0.0001992942,0.0003395971],"category_scores_gemma":[0.0009866339,0.0003136946,0.0004115851,0.00158908,0.0001365018,0.00008021454,0.0001864183,0.0003407114,0.00001960435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001443493,"about_ca_system_score_gemma":0.0004111606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009668714,"about_ca_topic_score_gemma":0.00194327,"domain_scores_codex":[0.9957713,0.001024995,0.001124403,0.0009790149,0.0005747715,0.0005255245],"domain_scores_gemma":[0.99248,0.005485137,0.0004999553,0.0008186844,0.0003243344,0.0003919326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"nonrandomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.09828147,0.2317836,0.2224895,0.0001169432,0.04773564,0.03974742,0.07777256,0.008016547,0.1502319,0.00006022982,0.06216861,0.06159557],"study_design_scores_gemma":[0.4692138,0.2657828,0.03845559,0.00005489431,0.07500599,0.0001201922,0.03981601,0.05219236,0.04461325,0.00005485919,0.01345688,0.001233314],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861493,0.0001586748,0.002126266,0.003377292,0.0002978569,0.007398217,0.0002993689,0.0001240147,0.00006906631],"genre_scores_gemma":[0.993538,0.00004837973,0.0005012117,0.0035681,0.0004173614,0.001692664,0.0001540969,0.00007489823,0.000005315796],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3709324,"threshold_uncertainty_score":0.9999315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1055195736780051,"score_gpt":0.3849784594191705,"score_spread":0.2794588857411654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}