{"id":"W3043701315","doi":"10.1093/neuonc/noaa168","title":"CODEL: phase III study of RT, RT + TMZ, or TMZ for newly diagnosed 1p/19q codeleted oligodendroglioma. Analysis from the initial study design","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Cancer Institute; ECOG-ACRIN Cancer Research Group; National Institutes of Health; American College of Radiology Imaging Network; Alliance for Clinical Trials in Oncology Foundation","keywords":"Oligodendroglioma; Medicine; Oncology; Phases of clinical research; Internal medicine; Nuclear medicine; Glioma; Cancer research; Chemotherapy; Astrocytoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00194281,0.001261866,0.001906829,0.0004087573,0.0002873503,0.0007953297,0.0009701345,0.0009337986,0.004802931],"category_scores_gemma":[0.001288517,0.0004947287,0.001205002,0.0004007467,0.0007022046,0.0003876237,0.0004560022,0.001410099,0.0008208887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001086694,"about_ca_system_score_gemma":0.001800721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001217119,"about_ca_topic_score_gemma":0.003708873,"domain_scores_codex":[0.9991703,0.0005585022,0.00002352914,0.0000863476,0.00008172764,0.00007959365],"domain_scores_gemma":[0.999193,0.0001491945,0.0002136453,0.00006113765,0.00004672616,0.0003363301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9059044,0.01353738,0.003759418,0.001454685,0.001610467,0.0001279529,0.0001071122,0.001415766,0.02261657,0.000280266,0.003586926,0.04559903],"study_design_scores_gemma":[0.8971255,0.09267044,0.005307307,0.00003044472,0.0004759381,0.0001101905,0.00001377249,0.0005743316,0.001091497,0.0001297019,0.002452791,0.00001807758],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9734763,0.003969734,0.002277683,0.0007565135,0.0002514501,0.01152206,0.004699528,0.0002162802,0.002830343],"genre_scores_gemma":[0.9612424,0.002975306,0.00507694,0.00149277,0.0003306851,0.01798719,0.004735754,0.00007778789,0.006081122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004802931,"threshold_uncertainty_score":0.01606745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1055195736780051,"score_gpt":0.3849784594191705,"score_spread":0.2794588857411654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}