{"id":"W3043863632","doi":"10.1093/brain/awaa145","title":"The apparently milder course of multiple sclerosis: changes in the diagnostic criteria, therapy and natural history","year":2020,"lang":"en","type":"review","venue":"Brain","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Multiple sclerosis; Medicine; Natural history; Disease; Demyelinating disease; McDonald criteria; Clinically isolated syndrome; Population; Pediatrics; Clinical trial; Epidemiology; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004340129,0.0003215451,0.0006249743,0.001969698,0.0003870796,0.001095856,0.0006563775,0.001142946,0.0007595453],"category_scores_gemma":[0.01308984,0.000191462,0.0002598119,0.001387297,0.002021897,0.001742551,0.0006240023,0.001745803,0.000307497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002871128,"about_ca_system_score_gemma":0.001124419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003034919,"about_ca_topic_score_gemma":0.002468433,"domain_scores_codex":[0.9972892,0.001221031,0.0003283851,0.0004013781,0.0006601615,0.00009984575],"domain_scores_gemma":[0.9929261,0.002506528,0.001816328,0.0003616619,0.00147511,0.0009143229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001275706,0.0006046346,0.2233874,0.002012335,0.0002920768,0.002836506,0.002154088,0.0008013996,0.01261446,0.01294879,0.01717216,0.7239004],"study_design_scores_gemma":[0.0001490828,0.0009906791,0.8424413,0.001443358,0.0001723776,0.02761877,0.001652731,0.001801043,0.001978395,0.01567611,0.1059068,0.000169406],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.4379019,0.4452321,0.01237497,0.08795537,0.002388072,0.0001596382,0.0005212844,0.000193116,0.0132735],"genre_scores_gemma":[0.8784679,0.08609767,0.009361663,0.01580855,0.007754395,0.0001368403,0.0004552172,0.00007972807,0.001837989],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004340129,"threshold_uncertainty_score":0.02295303,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1863525198484261,"score_gpt":0.3726912231947798,"score_spread":0.1863387033463537,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}