{"id":"W3043951483","doi":"10.1200/jco.19.02427","title":"Overestimation of Late Distant Recurrences in High-Risk Patients With ER-Positive Breast Cancer: Validity and Accuracy of the CTS5 Risk Score in the TEAM and IDEAL Trials","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Medicine; Breast cancer; Hazard ratio; Internal medicine; Clinical trial; Cancer; Surgery; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001767034,0.00009239517,0.0006815179,0.0000179368,0.00003220276,0.000004749381,0.0001234496,0.0001095061,0.000001819707],"category_scores_gemma":[0.003520434,0.00004311251,0.00008628238,0.00009011179,0.0003019643,0.00001112678,0.00007525374,0.0002817897,3.187523e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002118884,"about_ca_system_score_gemma":0.0002812635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006665884,"about_ca_topic_score_gemma":0.001133317,"domain_scores_codex":[0.997234,0.001353003,0.001030508,0.000140828,0.0001571837,0.00008451309],"domain_scores_gemma":[0.9957233,0.001576033,0.002409877,0.00008126813,0.0001643258,0.00004516041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004607763,0.0002788464,0.9603038,0.00001438456,0.0001362277,0.000002011019,0.0003561934,0.00007554264,0.00004356119,0.000008658165,0.00009935235,0.0340736],"study_design_scores_gemma":[0.005174055,0.002608041,0.9911433,0.0001035569,0.0002194347,0.00000467096,0.0001302962,0.00002084803,0.000196839,0.0002790912,0.00007526815,0.0000445663],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963733,0.0004975231,0.00001809341,0.002479385,0.0001249552,0.0002144133,0.0002764591,3.92122e-7,0.00001546648],"genre_scores_gemma":[0.9957573,0.003808902,0.0001467101,0.0001515486,0.000122956,0.000004681941,0.000004135923,0.000003443836,2.893638e-7],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03402904,"threshold_uncertainty_score":0.4214543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07562327189543909,"score_gpt":0.4009059600004262,"score_spread":0.3252826881049871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}