{"id":"W3044035113","doi":"10.3389/fendo.2020.00455","title":"Genetics of Hypertriglyceridemia","year":2020,"lang":"en","type":"review","venue":"Frontiers in Endocrinology","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":252,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Genetics; Hypertriglyceridemia; Biology; Genetic predisposition; Allele; Phenotype; Candidate gene; Single-nucleotide polymorphism; International HapMap Project; Gene; Genotype; Haplotype; Triglyceride; Endocrinology; Cholesterol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00004886716,0.0003472875,0.00356839,0.0005004589,0.00001167756,0.000002444001,0.0002652223,0.0003554026,0.00005157137],"category_scores_gemma":[0.000213968,0.0002893185,0.0004525474,0.0004648706,0.0002121033,0.00001891916,0.0001233987,0.0006068375,0.00003455976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007176505,"about_ca_system_score_gemma":0.0005296682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001417411,"about_ca_topic_score_gemma":0.00000118339,"domain_scores_codex":[0.9980161,0.0001282878,0.0008161518,0.0004387664,0.0001497787,0.0004509201],"domain_scores_gemma":[0.9990512,0.00005709622,0.0002664829,0.0004651297,0.00003322209,0.0001269068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000353794,0.00005697225,0.001007903,0.007995061,0.0002033224,0.0001671725,0.00003287512,2.821656e-7,4.243079e-7,0.0001732554,0.01696654,0.9733608],"study_design_scores_gemma":[0.0009092945,0.0001059988,0.00004827131,0.001081305,0.001086181,0.000193335,0.00005128112,0.000006994529,0.000004807507,0.0001043031,0.9962136,0.0001946969],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000008223761,0.9933066,0.000257582,0.0001099971,0.002307363,0.0006791549,0.00003406232,0.00003709062,0.003259943],"genre_scores_gemma":[0.000006990822,0.990337,0.008738501,0.0001695922,0.000303392,0.00005659538,0.0000793887,0.00005811488,0.0002503983],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.979247,"threshold_uncertainty_score":0.9999559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03723768484115033,"score_gpt":0.3278447073268885,"score_spread":0.2906070224857382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}