{"id":"W3044202699","doi":"10.1038/s41598-020-69524-8","title":"Age-dependent regional retinal nerve fibre changes in SIX1/SIX6 polymorphism","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Alcon Research Institute; Edith Cowan University; Wellcome Trust; Ophthalmic Research Institute of Australia; Raine Medical Research Foundation; Curtin University of Technology; European Commission; University of Notre Dame Australia; Murdoch University; Fight for Sight UK; National Health and Medical Research Council; Women and Infants Research Foundation; National Institute for Health and Care Research; King's College London; Medical Research Council; University of Notre Dame; Canadian Institutes of Health Research; Wellcome","keywords":"Nerve fibre layer; Allele; Retinal; Cohort; Glaucoma; Medicine; Polymorphism (computer science); Ophthalmology; Gene; Biology; Genetics; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000319119,0.0002895468,0.000261639,0.0004425223,0.0002122795,0.0002319452,0.0001741351,0.0002910536,0.004267483],"category_scores_gemma":[0.0007414522,0.00009924258,0.0004229181,0.0003793589,0.000129977,0.0001627499,0.000156958,0.0002549488,0.000364277],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001028633,"about_ca_system_score_gemma":0.00007481154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00110347,"about_ca_topic_score_gemma":0.001549036,"domain_scores_codex":[0.9998079,0.00004006936,0.00002890716,0.00006745684,0.00003428145,0.00002128356],"domain_scores_gemma":[0.9993501,0.0001305611,0.0003280873,0.00005755303,0.00006379094,0.00006996536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003371332,0.0001103867,0.8565635,0.0002239017,0.0004292963,0.00237834,0.000554382,0.0003373443,0.1158915,0.0003740875,0.0005725454,0.01919348],"study_design_scores_gemma":[0.00001357987,0.0001762458,0.9945374,0.00001306788,0.00007082581,0.001772127,0.00005742255,0.000215468,0.002369987,0.0001387734,0.0006276627,0.000007512328],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972698,0.0007796179,0.0006553002,0.00005309426,0.00001862451,0.000008993814,0.0005002698,0.00001282395,0.000701438],"genre_scores_gemma":[0.9981816,0.0002104354,0.0004698984,0.0000297456,0.0000157245,0.000008223099,0.0003804785,0.000008089854,0.0006958793],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004267483,"threshold_uncertainty_score":0.01427615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02618194590168916,"score_gpt":0.2557899460850128,"score_spread":0.2296080001833237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}