{"id":"W3044581296","doi":"10.1007/s13105-020-00756-y","title":"Obesity of mice lacking VAP-1/SSAO by Aoc3 gene deletion is reproduced in mice expressing a mutated vascular adhesion protein-1 (VAP-1) devoid of amine oxidase activity","year":2020,"lang":"en","type":"article","venue":"Journal of Physiology and Biochemistry","topic":"Microbial metabolism and enzyme function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Endocrinology; Internal medicine; Adipose tissue; Amine oxidase; Downregulation and upregulation; Biology; Insulin; Chemistry; Gene; Biochemistry; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000284326,0.0001695836,0.000391158,0.0000354754,0.00004160447,0.000004549393,0.0001365941,0.000269165,0.00001183289],"category_scores_gemma":[0.0002182041,0.0001543948,0.0001295546,0.0001314027,0.0001077793,0.00001680703,0.000090724,0.0002159469,3.013373e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001187388,"about_ca_system_score_gemma":0.00007273963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002883781,"about_ca_topic_score_gemma":8.142919e-7,"domain_scores_codex":[0.9988216,0.0001240906,0.0004418428,0.0003416208,0.000108784,0.0001621236],"domain_scores_gemma":[0.9989167,0.00001321948,0.0006237503,0.0001699108,0.0001988499,0.0000775859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001040467,0.0002087533,0.0003254873,0.000383657,0.00007324265,0.000002846949,0.00008732068,0.00002182266,0.9970184,1.501821e-7,0.0004651478,0.0003726949],"study_design_scores_gemma":[0.00104718,0.0002770252,0.002094301,0.0001039899,0.00004883299,0.00002197538,0.00005269827,0.00003619167,0.996001,0.00001157599,0.0001648372,0.0001403628],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972414,0.002163182,0.0002664597,0.0001266893,0.0000479853,0.0001052358,0.00004172578,0.000003041265,0.000004267151],"genre_scores_gemma":[0.9986846,0.0003601974,0.0005533785,0.0001055922,0.0002184084,0.000002028877,0.00004802812,0.00001152006,0.00001623596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001802985,"threshold_uncertainty_score":0.6296039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007903496702202282,"score_gpt":0.2148836326222591,"score_spread":0.2069801359200568,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}