{"id":"W3044655181","doi":"10.1111/mmi.14575","title":"Activation of biosynthetic gene clusters by the global transcriptional regulator <i>TRI6</i> in <i>Fusarium graminearum</i>","year":2020,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Mycotoxins in Agriculture and Food","field":"Agricultural and Biological Sciences","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University; Agriculture and Agri-Food Canada","funders":"","keywords":"Biology; Trichothecene; Secondary metabolite; Transcriptome; Chromatin immunoprecipitation; Transcription factor; Gene cluster; Gene; Mutant; Genetics; Repressor; Gene expression; Fusarium; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001413756,0.0004527188,0.0003191589,0.0002732299,0.0001761165,0.0003142195,0.0002343277,0.000223728,0.0007537237],"category_scores_gemma":[0.0001386704,0.0001850058,0.0003594015,0.000222798,0.0002445618,0.0001987946,0.0003734982,0.0005189639,0.0003203575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005417254,"about_ca_system_score_gemma":0.0002298569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001221727,"about_ca_topic_score_gemma":0.001614389,"domain_scores_codex":[0.9997726,0.00002244798,0.00001871304,0.00008687589,0.00005146073,0.00004784821],"domain_scores_gemma":[0.9998388,0.00002786649,0.0000586971,0.00002071292,0.00001905738,0.00003489498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003596223,0.000004871216,0.0001038935,0.0000116274,0.000001165988,0.00001852438,0.00000888084,0.00002058897,0.9994198,0.0000260012,0.00001336088,0.0003352411],"study_design_scores_gemma":[0.000009733814,0.00009619784,0.01192411,0.000005816862,0.00001610397,0.0002049027,0.0000624293,0.001114623,0.9846457,0.0000602515,0.001850149,0.00001007678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871913,0.001636539,0.007813646,0.0001702273,0.00004777347,0.00003043639,0.001563641,0.0003115147,0.001234825],"genre_scores_gemma":[0.9901265,0.0004677193,0.004186328,0.0001590732,0.00001429007,0.00003909844,0.002557795,0.00008334861,0.002365781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001221727,"threshold_uncertainty_score":0.003930569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007631852090251483,"score_gpt":0.1757147553228653,"score_spread":0.1680829032326138,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}