{"id":"W3044655181","doi":"10.1111/mmi.14575","title":"Activation of biosynthetic gene clusters by the global transcriptional regulator <i>TRI6</i> in <i>Fusarium graminearum</i>","year":2020,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Mycotoxins in Agriculture and Food","field":"Agricultural and Biological Sciences","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University; Agriculture and Agri-Food Canada","funders":"","keywords":"Biology; Trichothecene; Secondary metabolite; Transcriptome; Chromatin immunoprecipitation; Transcription factor; Gene cluster; Gene; Mutant; Genetics; Repressor; Gene expression; Fusarium; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009415029,0.0001415751,0.0001910056,0.000004951594,0.00004974898,0.00001230699,0.0003076728,0.0001607122,0.00003621948],"category_scores_gemma":[0.00002458919,0.00005072873,0.0001120287,0.0004107819,0.0001173443,0.00003092032,0.00004836178,0.0001194563,0.000008158704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002609244,"about_ca_system_score_gemma":0.000006778952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006964416,"about_ca_topic_score_gemma":0.00002376372,"domain_scores_codex":[0.9990208,0.0001513165,0.0002520143,0.0002819598,0.00006983589,0.0002241396],"domain_scores_gemma":[0.9997257,0.00004484394,0.00008726169,0.00005518664,0.00003688845,0.00005011192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005101169,0.00005890949,0.0003630576,0.000004344521,0.00001541727,0.000001877464,0.00004419745,0.00001618928,0.9968969,0.0003190177,0.0007722311,0.001456795],"study_design_scores_gemma":[0.00024994,0.0002383809,0.00169081,0.000004747226,0.00001280793,0.00002546046,0.00006205731,0.00002278084,0.9498386,0.0001250222,0.04759023,0.0001391707],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851207,0.0004935043,0.0001685803,0.01314859,0.00006656683,0.0002694331,0.0004923642,0.0000222001,0.0002181107],"genre_scores_gemma":[0.9950331,0.00001670751,0.0000915873,0.004140116,0.00005158146,0.000009773425,0.0006453601,9.700819e-7,0.00001073872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04705836,"threshold_uncertainty_score":0.2068658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007631852090251483,"score_gpt":0.1757147553228653,"score_spread":0.1680829032326138,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}