{"id":"W3044883025","doi":"10.7554/elife.55963","title":"Molecular determinants of large cargo transport into the nucleus","year":2020,"lang":"en","type":"article","venue":"eLife","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Deutsche Forschungsgemeinschaft","keywords":"Nucleus; Nuclear transport; Cell biology; Chemistry; Biology; Cell nucleus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003253543,0.0003551239,0.0003848736,0.0001765817,0.0002416898,0.0007669061,0.0002836967,0.0003592075,0.001336561],"category_scores_gemma":[0.001146519,0.0003019247,0.000274506,0.0001415813,0.0005821841,0.0005461143,0.0003788529,0.0006425492,0.0003361255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001023171,"about_ca_system_score_gemma":0.0003965614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009535936,"about_ca_topic_score_gemma":0.0006389892,"domain_scores_codex":[0.9998083,0.00002939444,0.00001538927,0.00005095516,0.00005926283,0.00003681295],"domain_scores_gemma":[0.9996135,0.0001740524,0.00008123707,0.0000376886,0.00003404527,0.0000594863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002077401,0.00003124793,0.001582896,0.00006006217,0.000009763367,0.0001318154,0.00004165308,0.01198789,0.9822389,0.002428052,0.00005080289,0.001229293],"study_design_scores_gemma":[0.00002894986,0.0001854634,0.007276878,0.0000107618,0.0000188006,0.0003076747,0.0001427051,0.06641991,0.9223865,0.00204688,0.001138785,0.00003670581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995881,0.0001811253,0.002941827,0.000057413,0.000007070056,0.000008902934,0.00007056318,0.0000453891,0.0008066538],"genre_scores_gemma":[0.9984995,0.0001089494,0.001021755,0.000007729323,0.000001266348,0.00001047017,0.00007095365,0.00002010992,0.0002592967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001336561,"threshold_uncertainty_score":0.007423699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0056128847663513,"score_gpt":0.2293506179416216,"score_spread":0.2237377331752703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}