{"id":"W3045184436","doi":"10.1038/s41467-020-17560-3","title":"Neuroligin 2 regulates absence seizures and behavioral arrests through GABAergic transmission within the thalamocortical circuitry","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Neuroligin; GABAergic; Neuroscience; Transmission (telecommunications); Neurotransmission; Biology; Computer science; Excitatory postsynaptic potential; Inhibitory postsynaptic potential; Genetics; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005628256,0.0004397853,0.0001281937,0.0002166477,0.0001263598,0.0002365561,0.0001574875,0.0002050736,0.0005065934],"category_scores_gemma":[0.00006774835,0.000121632,0.0001561568,0.00005569366,0.0002986057,0.0001236235,0.0002037541,0.0003077724,0.000115512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003032514,"about_ca_system_score_gemma":0.0001949531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001442864,"about_ca_topic_score_gemma":0.003611697,"domain_scores_codex":[0.9999388,0.000008526911,0.000004744275,0.00001590031,0.00001705077,0.00001495375],"domain_scores_gemma":[0.9999392,0.000003836939,0.00002964616,0.000003095311,0.000005199559,0.00001896643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009438986,0.00001208662,0.0009832573,0.00001767702,0.000006279215,0.0002834567,0.00001802829,0.00008191377,0.9976036,0.0001519837,0.00003326621,0.0007140668],"study_design_scores_gemma":[0.0001058999,0.0005198737,0.1451901,0.00002780574,0.0001171698,0.00275152,0.0002849879,0.003251418,0.8427196,0.0004705162,0.004543738,0.00001748072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973803,0.0004421314,0.0007831584,0.00006398225,0.00000831026,0.000005007197,0.00009227945,0.00003562151,0.001189164],"genre_scores_gemma":[0.9978821,0.0003460046,0.000385427,0.00002455796,0.000002901736,0.000009215244,0.00009574387,0.000008385663,0.001245713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001442864,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1081011742581725,"score_gpt":0.4023077975696295,"score_spread":0.294206623311457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}