{"id":"W3045276811","doi":"10.1093/infdis/jiaa438","title":"Efficacy of Antigonococcal CMP-Nonulosonate Therapeutics Require Cathelicidins","year":2020,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Cathelicidin; Microbiology; Chemistry; Sialyltransferase; Sialic acid; Antimicrobial; Antimicrobial peptides; Pharmacology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002702611,0.00034339,0.0003143064,0.000111798,0.00009851272,0.0003569126,0.0001819314,0.0003822364,0.0009411984],"category_scores_gemma":[0.0001817465,0.00007857459,0.0001784393,0.00008592401,0.0002866102,0.0002641761,0.0001984932,0.0008790809,0.000203275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002986903,"about_ca_system_score_gemma":0.0003781122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003158829,"about_ca_topic_score_gemma":0.0005152802,"domain_scores_codex":[0.9998125,0.00004749916,0.00001541688,0.00002013909,0.00005764213,0.00004673619],"domain_scores_gemma":[0.9998761,0.00002651832,0.00003494354,0.00001749752,0.00001839517,0.00002649448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000661549,0.0001742572,0.0004534529,0.0002830061,0.00002373434,0.00008849026,0.00002004152,0.0002281853,0.968456,0.0004997764,0.0002836737,0.02882785],"study_design_scores_gemma":[0.0002371828,0.005824917,0.008758966,0.00008267915,0.00007975403,0.0007799258,0.0000573258,0.001518275,0.9666986,0.0003587414,0.01559163,0.00001207034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9579695,0.0333141,0.003257596,0.0007174637,0.0001530566,0.0001285331,0.0003319166,0.000158209,0.003969504],"genre_scores_gemma":[0.9906012,0.005861691,0.001835816,0.0002200444,0.00003982834,0.00005719026,0.0002038179,0.000008134086,0.00117225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009411984,"threshold_uncertainty_score":0.003148556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03386357036283273,"score_gpt":0.3056019424968004,"score_spread":0.2717383721339677,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}