{"id":"W3045482742","doi":"10.1111/imm.13241","title":"Quantifying immunoregulation by autoantigen‐specific T‐regulatory type 1 cells in mice with simultaneous hepatic and extra‐hepatic autoimmune disorders","year":2020,"lang":"en","type":"article","venue":"Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; McGill University","funders":"Institute of Infection and Immunity; Diabetes Canada; Generalitat de Catalunya; Natural Sciences and Engineering Research Council of Canada; Multiple Sclerosis Society of Canada; Crohn's and Colitis Foundation of Canada","keywords":"Experimental autoimmune encephalomyelitis; Autoimmunity; Immunology; Biology; Epitope; T cell; Autoimmune disease; Regulatory T cell; Inflammation; Antigen; Immune system; Antibody; IL-2 receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002431762,0.000608788,0.0009288381,0.0002639003,0.000357323,0.00004394813,0.0005381745,0.000734187,0.0004839523],"category_scores_gemma":[0.00008499035,0.0005669192,0.00009899838,0.000614349,0.001133169,0.0002207109,0.0002273381,0.0009636905,0.0006430365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001037617,"about_ca_system_score_gemma":0.0001194536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005806849,"about_ca_topic_score_gemma":0.0002115523,"domain_scores_codex":[0.9965038,0.0005855103,0.000874746,0.0009585287,0.00008412321,0.0009933274],"domain_scores_gemma":[0.9983487,0.0005704672,0.0003669359,0.0005674973,0.00009745536,0.00004891831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001153414,0.0002716013,0.004068919,0.00006347,0.000345741,0.0000373665,0.001871494,0.0001936114,0.9798512,0.0002891692,0.0003913005,0.01146269],"study_design_scores_gemma":[0.01479101,0.004782917,0.03724198,0.0003034335,0.0002948509,0.000473675,0.003017209,0.002260452,0.8037665,0.0002980109,0.1300167,0.002753169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9434708,0.05339013,0.0002910075,0.000790321,0.0009565973,0.0006379766,0.00002694808,0.0002674694,0.0001687495],"genre_scores_gemma":[0.9950434,0.003438442,0.000228586,0.0002402883,0.00002396745,0.00003681558,0.0002855985,0.00009120032,0.0006117051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1760847,"threshold_uncertainty_score":0.9996783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01237713894401451,"score_gpt":0.2123820811575488,"score_spread":0.2000049422135343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}