{"id":"W3045515457","doi":"10.4049/jimmunol.2000338","title":"Identification of a Protective <i>Leishmania</i> Antigen Dihydrolipoyl Dehydrogenase and Its Responding CD4+ T Cells at Clonal Level","year":2020,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Biology; Leishmania major; Amastigote; Cutaneous leishmaniasis; Antigen; Immunology; Dihydrolipoamide dehydrogenase; Leishmania; Immunity; Effector; Virology; Vaccination; T cell; Leishmaniasis; Microbiology; Immune system; Parasite hosting; Pyruvate dehydrogenase complex; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009817287,0.0001787123,0.0001237533,0.0001216024,0.0001111957,0.0002455209,0.0001257456,0.0002458643,0.001481274],"category_scores_gemma":[0.00008761764,0.00008158169,0.0001330869,0.00005414491,0.0001127422,0.0001474917,0.0001523433,0.0004313331,0.0004253259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000168369,"about_ca_system_score_gemma":0.00009579772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001504867,"about_ca_topic_score_gemma":0.0001697827,"domain_scores_codex":[0.9999285,0.000009686642,0.00000454041,0.00002193938,0.00001116402,0.00002415607],"domain_scores_gemma":[0.9999261,0.00001457596,0.00001315154,0.000008483618,0.00001336319,0.00002437344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003812017,0.00001641047,0.0004752441,0.000009691286,0.000001008554,0.00002496391,0.000007821285,0.00002417858,0.9984901,0.00003145614,0.00001498248,0.0008661849],"study_design_scores_gemma":[0.00004601659,0.001065407,0.01796007,0.00001344091,0.00002674621,0.001061856,0.0001066216,0.002348046,0.9740005,0.0002175083,0.003148934,0.000005041232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946322,0.0003356269,0.003414945,0.00007343398,0.0000161705,0.00003975708,0.0001144752,0.00003975033,0.001333501],"genre_scores_gemma":[0.9967097,0.0001216682,0.001709555,0.00006652599,0.00001690978,0.00001962944,0.0002018507,0.000008399473,0.001145808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001481274,"threshold_uncertainty_score":0.004955351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04762571229935222,"score_gpt":0.2991780510721931,"score_spread":0.2515523387728409,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}